Background The gastrointestinal peptide hormone ghrelin was discovered in 1999 as the
endogenous ligand of the growth hormone secretagogue receptor. Increasing evidence …

The a 28-amino acid peptide ghrelin was discovered in 1999 as a growth hormone (GH)
releasing peptide. Soon after its discovery, ghrelin was found to increase body weight and …

Ghrelin is a peptide predominantly produced by the stomach. Ghrelin displays strong GH-
releasing activity. This activity is mediated by the activation of the so-called GH …

Mammals respond to reduced food availability by becoming more wakeful and active, yet the
central pathways regulating arousal and instinctual motor programs (such as food seeking) …

Ghrelin, an acylated upper gastrointestinal peptide, is the only known orexigenic hormone.
Considerable evidence implicates ghrelin in mealtime hunger and meal initiation …

Ghrelin is an orexigenic hormone that is implicated in meal initiation, in part because
circulating levels rise before meals. Because previous human studies have examined …

Mistlberger, RE Neurobiology of food anticipatory circadian rhythms. Physiol Behav 00 (00):
000–000, 2011. Circadian rhythms in mammals can be entrained by daily schedules of light …

Ghrelin, a peptide hormone predominantly produced by the stomach, was isolated as the
endogenous ligand for the growth hormone secretagogue receptor. Ghrelin is a potent …

In humans, growth hormone (GH) is secreted from the anterior pituitary in a pulsatile pattern.
The traditional view is that this secretory pattern is driven by two counter regulatory …

Plasma ghrelin levels rise before meals and fall rapidly afterward. If ghrelin is a
physiological meal-initiation signal, then a large oral caloric load should suppress ghrelin …