Piperidines are among the most important synthetic fragments for designing drugs and play
a significant role in the pharmaceutical industry. Their derivatives are present in more than …

A Cu-catalyzed, easily scalable one-pot synthesis of fused pyridines by the reaction of cyclic
ketones with propargylamine is described. The protocol was optimized based on the results …

Lipoxins are an important class of pro-resolving mediators that play a crucial role in the
resolution of inflammation. Thus, the synthesis of more chemically and metabolically stable …

The possibility of deoxofluorination of β-keto esters using SF 4 was investigated. The scope
and limitation of the reaction were determined. The efficient method for the synthesis of β, β …

Herein, we describe a general and selective deprotonation functionalization reaction of
tetrahydroquinolines at the 4–position using organolithiums and phosphoramide ligands. In …

A previously unknown reduction of carbonyl compounds with dicyclopentylzinc is reported.
Aldehydes react in mild conditions yielding corresponding primary alcohols and …

Synthesis of amino acids with isolated saturated (hetero) carbocyclic scaffold was disclosed.
The method relied on Suzuki cross-coupling reaction of heteroacycloalkene triflates and N …

A new, high-yielding, and practical method for synthesis of 1-methyl-3-(trifluoromethyl)-1 H-
pyrazole and 1-methyl-5-(trifluoromethyl)-1 H-pyrazole, key intermediates for important …

Reactions of five-and six-membered cyclic β-alkoxyvinyl α-keto esters and NCC-
binucleophiles are described. The following binucleophiles were studied: heteroaromatic …

An approach to 1, 3-disubstitued bicyclo [2.1. 0] pentane (housane) derivatives was
developed. The method relied on lithium bis (trimethylsilyl) amide-mediated intramolecular …