Principles of organelle positioning in motile and non-motile cells

J Kroll, J Renkawitz - EMBO reports, 2024 - embopress.org
Cells are equipped with asymmetrically localised and functionally specialised components,
including cytoskeletal structures and organelles. Positioning these components to specific …

The biophysics of cell motility through mechanochemically challenging environments

AP Caruso, JS Logue - Current Opinion in Cell Biology, 2024 - Elsevier
Challenging mechanochemical environments (ie, with varied mechanical and adhesive
properties) are now known to induce a wide range of adaptive phenomena in motile cells …

Global coordination of protrusive forces in migrating immune cells

P Reis-Rodrigues, N Canigova, MJ Avellaneda… - bioRxiv, 2024 - biorxiv.org
Efficient immune responses rely on the capacity of leukocytes to traverse diverse and
complex tissues. To meet such changing environmental conditions, leukocytes usually adopt …

Mechanical remodeling of nuclear biomolecular condensates

G Soggia, Y ElMaghloob, AK Boromangnaeva… - …, 2025 - journals.physiology.org
Organism health relies on cell proliferation, migration, and differentiation. These universal
processes depend on cytoplasmic reorganization driven notably by the cytoskeleton and its …

A protein kinase A-regulated centrosomal actin pool sets the threshold for T cell polarization

M Simao, F Régnier, C Randriamampita - bioRxiv, 2024 - biorxiv.org
T lymphocyte migration triggered by chemokine stimulation is preceded by cell polarization.
The acquisition of this asymmetry requires a profound cell rearrangement, particularly of the …

Cell type-dependent functions of centrosome linker components and their role in centrosome clustering and mitotic spindle formation

L Theile - 2024 - archiv.ub.uni-heidelberg.de
The centrosome is the main microtubule organizing center (MTOC) of animal cells. It
consists of mother and daughter centrioles that are surrounded by the so called …