NETosis is a type of regulated cell death dependent on the formation of neutrophil
extracellular traps (NET), where net-like structures of decondensed chromatin and proteases …

Abstract Peptidylarginine deaminase 4 (PAD4) is a crucial post-translational modifying
enzyme catalyzing the conversion of arginine into citrulline residues, and mediating the …

Abstract Peptidylarginine deiminase 4 (PAD4) is a nuclear citrullinating enzyme that is
critically involved in the release of decondensed chromatin from neutrophils as neutrophil …

Protein arginine deiminases (PAD) 4 is an enzyme that catalyzes citrullination of protein and
its role in autoimmune diseases has been established through clinical genetics and gene …

Biomaterial implantation triggers an immune response initially predominated by neutrophils,
which activate an inflammatory cascade by producing cytokines, enzymes, immune cell …

Neutrophils predominate the early inflammatory response to tissue injury and implantation of
biomaterials. Recent studies have shown that neutrophil activation can be regulated by …

Background: NETosis occurs in the context of infection or inflammation and results in the
expulsion of decondensed DNA filaments called NETs (Neutrophil Extracellular Traps) into …

Abstract Purpose of Review Antiphospholipid syndrome (APS) is a thrombo-inflammatory
disease that is primarily treated with anticoagulation. Better understanding the inflammatory …

Neutrophils are the most abundant type of white blood cells. Upon stimulation, they are able
to decondense and release their chromatin as neutrophil extracellular traps (NETs). This …

Infectious and inflammatory stimuli induce the release of neutrophil extracellular traps
(NETs), webs of cell‐free (cf) DNA complexed with histones and antimicrobial proteins, that …