Evaluation of the Anti-Leishmania mexicana and -Trypanosoma brucei Activity and Mode of Action of 4,4′-(Arylmethylene)bis(3-methyl-1-phenyl-1H-pyrazol-5-ol)

O Barreiro-Costa, C Quiroga Lozano, E Muñoz… - Biomedicines, 2022 - mdpi.com
Trypanosomiasis and leishmaniasis are neglected infections caused by trypanosomatid
parasites. The first-line treatments have many adverse effects, high costs, and are prone to …

Direct access to spirooxindole dihydropyrrole fused pyrazolones and bis-spiropyrazolone derivatives

PK Warghude, A Bhowmick, RG Bhat - Tetrahedron Letters, 2022 - Elsevier
A highly regio-and diastereo-selective [3+ 2] annulation of Morita–Baylis–Hillman
carbonates of isatins/pyrazolones with pyrazolone derived ketimines has been developed to …

Stereoselective and efficient chemical transformation of aldehydes and two molecules of pyrazolin-5-one into bis (spiropyrazolone) cyclopropanes under a column …

MN Elinson, YE Ryzhkova, FV Ryzhkov… - Monatshefte für Chemie …, 2023 - Springer
The new type of chemical one-pot Knoevenagel-Michael reaction with following
stereoselective NBS induced cyclization was found: the direct chemical one-pot …

Synthesis and Evaluation of Thiomethyl-Substituted (4Z)-4-[(Pyrazol-4-yl)methylene]pyrazolone as an Optical Chemosensor

PV Mazón Ayala, JC Romero-Benavides… - Chemistry …, 2023 - mdpi.com
Developing colorimetric devices for detecting chemical species is essential in many fields;
nevertheless, developing effective chemosensors for many heavy and transition metal ions …

Beta Lactams Anticancer Effect on Human Breast Cancer, MCF-7 Cell Line

A Abalos - 2024 - search.proquest.com
Cancer is a disease where abnormal cells replicate uncontrollably in that same region
and/or other parts of the body. One in eight women are diagnosed with breast cancer, thus …

[PDF][PDF] Synthesis and Evaluation of Thiomethyl Substituted (4Z)-4-[(Pyrazol-4-yl) methylene] pyrazolone as an Optical Chemosensor

PVM Ayala, JC Romero-Benavides, J Heredia-Moya - 2023 - sciforum.net
Developing colorimetric devices for detecting chemical species is essential in many fields;
nevertheless, developing effective chemosensors for many heavy and transition metal ions …

SYNTHESIS AND ESTABLISHMENT OF THE STRUCTURE OF VINYL ETHER OF MONOSUBSTITUTED CYCLOPROPANECARBOXYLIC ACID

RZ Shahnazarli - Processes of Petrochemistry and Oil Refining, 2025 - ppor.az
There have been synthesized and characterized the cyclopropane-containing vinyl ethers
with carboxyl and ethoxycarbonyl functional substituents in a three-membered cycle–2 …

Synthesis of 4-Arylallylidenepyrazolone Derivatives

E Aguilar-Llanos, JC Romero-Benavides… - Chemistry …, 2021 - mdpi.com
Pyrazoles and their derivatives have attracted particular attention because they have a wide
variety of biological activities, and recently, we found that 4, 4'-(arylmethylene)-bis-(1-phenyl …

New methods for organocatalyzed asymmetric synthesis of spirocyclic pyrazolones from pyrazole-4, 5-diones and n-boc protected pyrazolinone ketimines

M Gil Ordóñez - 2022 - uvadoc.uva.es
Pyrazole derivatives are an interesting class of heterocycles known for the wide range of
applications they enable. Among all of them, spirocyclic pyrazolones and 4-amino-5 …