Intense efforts to detect, diagnose, and analyze the kinetic and structural properties of
amyloid fibrils have generated a powerful toolkit of amyloid-specific molecular probes. Since …

Because understanding amyloid fibrillation in molecular detail is essential for development
of strategies to control amyloid formation and overcome neurodegenerative disorders …

Thioflavine T (ThT) associates rapidly with aggregated fibrils of the synthetic β/A4‐derived
peptides β (1–28) and β (1–40), giving rise to a new excitation (ex)(absorption) maximum at …

Publisher Summary Despite the presence of a significant amount of carbohydrate in these
fibrils, the staining reaction was eventually shown to be because of the protein component …

Acetylcholinesterase (AChE), an important component of cholinergic synapses, colocalizes
with amyloid-β peptide (Aβ) deposits of Alzheimer's brain. We report here that bovine brain …

Nanofiber structures of some peptides and proteins as biological materials have been
studied extensively, but their molecular mechanism of self-assembly and reassembly still …

Curcumin has a long history of use as a traditional remedy and food in Asia. Many studies
have reported that curcumin has various beneficial properties, such as antioxidant …

The aggregation of β-amyloid (1–40)(Aβ) induced by human recombinant
acetylcholinesterase (HuAChE) was studied by means of circular dichroism (CD) and by …

Research on the human microbiome has established that commensal and pathogenic
bacteria can influence obesity, cancer, and autoimmunity through mechanisms mostly …

Background: Amyloid plaques composed of the fibrillar form of the amyloid-β protein (Aβ)
are the defining neuropathological feature of Alzheimer's disease (AD). A detailed …