The potential of plant phenolics in prevention and therapy of skin disorders

M Działo, J Mierziak, U Korzun, M Preisner… - International journal of …, 2016 - mdpi.com
Phenolic compounds constitute a group of secondary metabolites which have important
functions in plants. Besides the beneficial effects on the plant host, phenolic metabolites …

Role of phenolic compounds in human disease: current knowledge and future prospects

MM Rahman, MS Rahaman, MR Islam, F Rahman… - Molecules, 2021 - mdpi.com
Inflammation is a natural protective mechanism that occurs when the body's tissue
homeostatic mechanisms are disrupted by biotic, physical, or chemical agents. The immune …

[HTML][HTML] CD44 assists the topical anti-psoriatic efficacy of curcumin-loaded hyaluronan-modified ethosomes: a new strategy for clustering drug in inflammatory skin

Y Zhang, Q Xia, Y Li, Z He, Z Li, T Guo, Z Wu… - Theranostics, 2019 - ncbi.nlm.nih.gov
Background: Psoriasis is a common chronic inflammatory skin disease. Its treatment is
challenged by the limited amount of drug reaching the inflamed skin. The overexpressed …

Curcumin as potential therapeutic natural product: a nanobiotechnological perspective

S Shome, AD Talukdar, MD Choudhury… - Journal of Pharmacy …, 2016 - academic.oup.com
Objectives Nanotechnology-based drug delivery systems can resolve the poor
bioavailability issue allied with curcumin. The therapeutic potential of curcumin can be …

[HTML][HTML] Emerging landscape in psoriasis management: from topical application to targeting biomolecules

VK Rapalli, G Singhvi, SK Dubey, G Gupta… - Biomedicine & …, 2018 - Elsevier
Psoriasis is a chronic autoimmune skin disorder affecting 2–3% of the world population. It
has characteristic features such as increased keratinocyte proliferation and production of …

Microalgae as potential anti-inflammatory natural product against human inflammatory skin diseases

WT Choo, ML Teoh, SM Phang, P Convey… - Frontiers in …, 2020 - frontiersin.org
The skin is the first line of defense against pathogen and other environmental pollutant. The
body is constantly exposed to reactive oxygen species (ROS) that stimulates inflammatory …

A new topical formulation for psoriasis: development of methotrexate-loaded nanostructured lipid carriers

MF Pinto, CC Moura, C Nunes, MA Segundo… - International journal of …, 2014 - Elsevier
The aim of the present work was to develop and assess the potential of nanostructured lipid
carriers (NLCs) loaded with methotrexate as a new approach for topical therapy of psoriasis …

Olive oil based methotrexate loaded topical nanoemulsion gel for the treatment of imiquimod induced psoriasis-like skin inflammation in an animal model

SA Rashid, S Bashir, F Naseem, A Farid, IA Rather… - Biology, 2021 - mdpi.com
Simple Summary Psoriasis, being chronic inflammatory illness, provoked by genetic and
environmental factors is linked to several other life-threatening diseases. Methotrexate is …

Nanomedicine-based drug targeting for psoriasis: potentials and emerging trends in nanoscale pharmacotherapy

M Rahman, S Akhter, J Ahmad, MZ Ahmad… - Expert opinion on …, 2015 - Taylor & Francis
Introduction: Psoriasis is a T-cell mediated autoimmune inflammatory skin disease
recognized by skin surface inflammation, epidermal proliferation, hyperkeratosis …

Perspective insights of small molecules, phytoconstituents and biologics in the management of psoriasis: A focus on targeting major inflammatory cytokine pathways

H Kadagothy, S Nene, E Amulya, G Vambhurkar… - European Journal of …, 2023 - Elsevier
Psoriasis is an enduring, pruritic and papulosquamous skin ailment that poses a significant
burden on public health. It is mainly characterized by hyperkeratosis, acanthosis …