Environmental enrichment consisting of social peers and novel objects is known to alter
neurobiological functioning and have an influence on the behavioral effects of drugs of …

Ethanol-induced behavioral sensitization (EBS) was first described in 1980, approximately
10 years after the phenomenon was described for psychostimulants. Ethanol acts on γ …

Environmental conditions, such as stress and environmental enrichment (EE), influence
predisposition to alcohol use/abuse; however, the underlying mechanisms remain unknown …

Drug addiction is a chronic neuropsychiatric disorder that escalates from an initial exposure
to drugs of abuse, such as cocaine, cannabis, or heroin, to compulsive drug-seeking and …

Elevated alcohol intake after abstinence is a key feature of the addiction process. Some
studies have shown that environmental enrichment (EE) affects ethanol intake and other …

Previous research from our laboratory has shown that exposure to chronic psychosocial
stress increased voluntary ethanol consumption and preference as well as acquisition of …

This study analyzed ethanol intake in male and female Wistar rats exposed to maternal
separation (MS) during infancy (postnatal days 1–21, PD1–21) and environmental …

Alcohol use disorder (AUD) is a public health issue that affects millions of people worldwide
leading to physical, mental and socio-economic consequences. While current treatments for …

Prenatal ethanol exposure (PEE) promotes ethanol consumption in the adolescent offspring
accompanied by the transcriptional regulation of kappa opioid receptor (KOR) system …

Background Behavioral sensitization induced by repeated ethanol (E t OH) exposure may
play a critical role in the development of alcohol dependence. Because recent data …