A PIANO (proper, insufficient, aberrant, and NO reprogramming) response to the Yamanaka factors in the initial stages of human iPSC reprogramming
K Hu - International Journal of Molecular Sciences, 2020 - mdpi.com
Yamanaka reprogramming is revolutionary but inefficient, slow, and stochastic. The
underlying molecular events for these mixed outcomes of induction of pluripotent stem cells …
underlying molecular events for these mixed outcomes of induction of pluripotent stem cells …
Quick, coordinated and authentic reprogramming of ribosome biogenesis during iPSC reprogramming
K Hu - Cells, 2020 - mdpi.com
Induction of pluripotent stem cells (iPSC) by OCT4 (octamer-binding transcription factor 4),
SOX2 (SR box 2), KLF4 (Krüppel-Like Factor 4), and MYC (cellular Myelocytomatosis, c …
SOX2 (SR box 2), KLF4 (Krüppel-Like Factor 4), and MYC (cellular Myelocytomatosis, c …
Attenuating iPSC reprogramming stress with dominant-negative BET peptides
Generation of induced pluripotent stem cells (iPSCs) is inefficient and stochastic. The
underlying causes for these deficiencies are elusive. Here, we showed that the …
underlying causes for these deficiencies are elusive. Here, we showed that the …
Rapamycin Treatment Is Beneficial for the Generation of Rabbit-Induced Pluripotent Stem-Like Cells
X Ren, W Lei, S Huang, D Shi, X Li - Cellular Reprogramming, 2022 - liebertpub.com
Autophagy could promote the generation of induced pluripotency stem cells (iPSCs) in
humans and mice. However, little was known whether it had similar effects in other species …
humans and mice. However, little was known whether it had similar effects in other species …
[PDF][PDF] Development of a self-sufficient and selectable reprogramming vector to convert human skin fibroblasts to neurons
E Campbell - 2022 - islandscholar.ca
Human neurons are complex cells that are valuable models when studying neurobiology;
however, they are difficult to obtain as they are post-mitotic and require invasive sampling …
however, they are difficult to obtain as they are post-mitotic and require invasive sampling …