HIV assembly and replication proceed through the formation of morphologically distinct
immature and mature viral capsids that are organized by the Gag polyprotein (immature) …

Like all retroviruses, the human immunodeficiency virus selectively packages two copies of
its unspliced RNA genome, both of which are utilized for strand-transfer-mediated …

A system for programmable export of RNA molecules from living cells would enable both
non-destructive monitoring of cell dynamics and engineering of cells capable of delivering …

The human immunodeficiency virus type 1 initially assembles and buds as an immature
particle that is organized by the viral Gag polyprotein. Gag is then proteolyzed to produce …

Assembly of human immunodeficiency virus type 1 is driven by oligomerization of the Gag
polyprotein at the plasma membrane of an infected cell, leading to membrane envelopment …

The major structural elements of retroviruses are contained in a single polyprotein, Gag,
which in human immunodeficiency virus type 1 (HIV‐1) comprises the MA, CA, spacer …

The duality of liquid-liquid phase separation (LLPS) of cellular components into
membraneless organelles defines the nucleation of both normal and disease processes …

HIV-1 Gag drives a number of events during the genesis of virions and is the only viral
protein required for the assembly of virus-like particles in vitro and in cells. Although a …

A single retroviral protein, Gag, is sufficient for virus particle assembly. While Gag is capable
of specifically packaging the genomic RNA into the particle, this RNA species is …

The HIV genome encodes a small number of viral proteins (ie, 16), invariably establishing
cooperative associations among HIV proteins and between HIV and host proteins, to invade …