Although fire is now rarely used in synthetic chemistry, it was not until Robert Bunsen
invented the burner in 1855 that the energy from this heat source could be applied to a …

In the electromagnetic spectrum, the microwave radiation region is located between infrared
radiation and radio waves. Microwaves have wavelengths of 1 mm±1 m, corresponding to …

The efficiency of microwave flash heating in accelerating organic transformations (reaction
times reduced from days and hours to minutes and seconds) has recently been proven in …

In both lead identification and lead optimization processes there is an acute need for new
organic small molecules. Traditional methods of organic synthesis are orders of magnitude …

Oxidative addition initiates most palladium-catalyzed cross-couplings [1] and is often rate-
limiting for reactions of aryl chlorides [2] and deactivated aryl bromides.[3] This addition …

A series of well-defined, air-and moisture-stable (NHC) Pd (allyl) Cl (NHC= N-heterocyclic
carbene) complexes has been used in several catalytic reactions: Suzuki− Miyaura cross …

A dirty word in synthesis: separation! The normally unavoidable separation at the end of
each reaction finds no friends among synthetic chemists and is often regarded as a technical …

The presence of heterocyclic moieties in all kinds of organic compounds of interest in
biology, pharmacology, optics, electronics, material sciences, and so on is sufficiently known …

Die offene Flamme konnte erst gezielt als Heizquelle für Reaktionsgefäße in der
Synthesechemie verwendet werden, nachdem Robert Bunsen 1855 den nach ihm …

The hydroformylation of decene-1 was studied in the presence of the fluorous-soluble P
[CH2CH2 (CF2) 5CF3] 3 modified rhodium catalyst at 100° C and 1.1 MPa of CO/H2 (1: 1) in …