Engineered biomaterial delivery strategies are used to reduce cardiotoxicity in osteosarcoma

Y Hou, J Wang, J Wang - Frontiers in Pharmacology, 2023 - frontiersin.org
Osteosarcoma (OS) is the most common malignant bone tumor in children and adolescents.
Chemotherapy drugs play an integral role in OS treatment. Preoperative neoadjuvant …

[HTML][HTML] Co-morbid intersections of cancer and cardiovascular disease and targets for natural drug action: Reprogramming of lipid metabolism

G Zhu, L Cao, J Wu, M Xu, Y Zhang, M Wu… - Biomedicine & …, 2024 - Elsevier
Cancer and cardiovascular diseases are major contributors to global morbidity and mortality,
and their seemingly separate pathologies are intricately intertwined. In the context of cancer …

[HTML][HTML] Berberine-loaded nanostructured lipid carriers mitigate warm hepatic ischemia/reperfusion-induced lesion through modulation of HMGB1/TLR4/NF-κB …

AM Gendy, MR Elnagar, MM Allam, MR Mousa… - Biomedicine & …, 2022 - Elsevier
Highlights•The nanostructured lipid carriers formula of berberine enhance its
efficiency.•Berberine-loaded nanostructured lipid carriers lessen warm hepatic …

Elucidating Therapeutic and Biological Potential of Berberis baluchistanica Ahrendt Bark, Leaf, and Root Extracts

Z Gul, A Akbar, SK Leghari - Frontiers in Microbiology, 2022 - frontiersin.org
Berberis baluchistanica Ahrendt is a medicinal plant known to have potential for the
treatment of various diseases. In the present study, the ethanolic extracts of the bark, leaves …

Potential Gonado-Protective Effect of Cichorium endivia and Its Major Phenolic Acids against Methotrexate-Induced Testicular Injury in Mice

EE Eltamany, EM Mosalam, ET Mehanna, BM Awad… - Biomedicines, 2022 - mdpi.com
Cichorium endivia L.(Asteraceae) is a wide edible plant that grows in the Mediterranean
region. In this study, a phytochemical investigation of C. endivia L. ethanolic extract led to …

Blending Ethnomedicine with Modern Technology—From Conventional to Tailored Products: Modulating Biopharmaceutical Properties of Berberis Extract by Solid …

N Sharma, K Vasisht, J Kaur, SK Sandhu… - Journal of Functional …, 2023 - mdpi.com
Drug-delivery systems employing phytopharmaceuticals based on the leads in traditional
knowledge offers not only an alternative but quicker and more economic strategy for drug …

Extract-mediated biosynthesis and characterization of gold nanoparticles: Exploring their protective effect against cyclophosphamide-induced oxidative stress in rat …

F Mobaraki, M Momeni, M Barghbani, BF Far… - Journal of Drug Delivery …, 2022 - Elsevier
The biosynthesis method is essential for minimizing toxic by-products caused by
conventional nanoparticle synthesis. Adding a surface biological coating to gold …

Zygo-Albuside A: New Saponin from Zygophyllum album L. with Significant Antioxidant, Anti-Inflammatory and Antiapoptotic Effects against Methotrexate-Induced …

RFA Abdelhameed, SA Fattah, ET Mehanna… - International Journal of …, 2022 - mdpi.com
Chemical investigation of the crude extract of the aerial part of Zygophyllum album L.(Z.
album) led to the isolation of a new saponin, Zygo-albuside A (7), together with seven known …

Extraction of flavonoids and phenolics from Berberis kongboensis fruit

X Chen, S Yang, H Yang, J Zhang, Y Huang… - Biomass Conversion …, 2024 - Springer
Response surface methodology was used to optimize the ultrasonic-assisted extraction
(UAE) of total flavonoids (TF) and total phenols (TP) from Berberis kongboensis fruit. Single …

[HTML][HTML] Induced resistance to ifosfamide in osteosarcoma cells suggests a more aggressive tumor profile

MT de Oliveira Rodrigues, LP da Silva… - … and Biophysics Reports, 2022 - Elsevier
Aims Osteosarcoma (OS) is the most common primary malignant bone sarcoma among
children and adolescents. Treatment is based on neo-adjuvant and adjuvant chemotherapy …