Preoperative chemotherapy for operable colon cancer: mature results of an international randomized controlled trial

D Morton, M Seymour, L Magill, K Handley… - Journal of clinical …, 2023 - ascopubs.org
PURPOSE Neoadjuvant chemotherapy (NAC) has potential advantages over standard
postoperative chemotherapy for locally advanced colon cancer but requires formal …

Neoadjuvant chemotherapy for early-stage colon cancer

A Audisio, R Fazio, V Daprà, I Assaf, A Hendlisz… - Cancer Treatment …, 2024 - Elsevier
Surgery with or without adjuvant chemotherapy is the standard treatment for early-stage
colon cancer. However, evidence has recently emerged for neoadjuvant chemotherapy, with …

Diagnostic performance of MRI and FDG PET/CT for preoperative locoregional staging of colon cancer: systematic review and meta-analysis

DJ Sikkenk, IJ Henskens, B van de Laar… - American Journal of …, 2024 - ajronline.org
BACKGROUND. CT is the standard-of-care test for preoperative locoregional staging of
colon cancer (CC) but has limited diagnostic performance. More accurate preoperative …

[HTML][HTML] Diagnostic accuracy of CT for local staging of colon cancer: A nationwide study in the Netherlands

J Shkurti, K van den Berg, FN van Erning… - European Journal of …, 2023 - Elsevier
Objective To determine the accuracy of computed tomography (CT)-based staging in
selecting high-risk colon cancer patients who would benefit from neoadjuvant chemotherapy …

Tumour deposits in colon cancer predict recurrence and reduced survival in a nationwide population-based study

F Jörgren, E Agger, ML Lydrup, P Buchwald - BJS open, 2023 - academic.oup.com
Background Tumour deposits are suggested to impact prognosis in colon cancer negatively.
This study assessed the impact of tumour deposits on oncological outcomes. Methods Data …

The role of neoadjuvant chemotherapy in patients with locally advanced colon cancer: A systematic review and meta-analysis

Z Liang, Z Li, Q Yang, J Feng, D Xiang, H Lyu… - Frontiers in …, 2022 - frontiersin.org
Background Controversy persists about neoadjuvant chemotherapy (NAC) within the field of
locally advanced colon cancer (LACC). The purpose of this study was to assess the existing …

Risk of Bowel Obstruction in Patients Undergoing Neoadjuvant Chemotherapy for High-risk Colon Cancer: A Nested Case-control–matched Analysis of an …

FOxTROT Collaborating Group - Annals of surgery, 2024 - journals.lww.com
Objective: This study aimed to identify risk criteria available before the point of treatment
initiation that can be used to stratify the risk of obstruction in patients undergoing …

Nationwide practice in CT-based preoperative staging of colon cancer and concordance with definitive pathology

DJ Sikkenk, JML Sijmons, TA Burghgraef… - European Journal of …, 2023 - Elsevier
Introduction In an era of exploring patient-tailored treatment options for colon cancer,
preoperative staging is increasingly important. This study aimed to evaluate completeness …

[PDF][PDF] Clinical evidence for the benefits of neoadjuvant chemotherapy and immunotherapy in colon cancer: a concise review

K Gupta, A Elfiky, E Patel - Discov Med, 2023 - scholar.archive.org
Neoadjuvant chemotherapy (NAC) has long been considered technically difficult in locally
advanced colon cancer (LACC). However, the introduction of oxaliplatin-based regimens led …

Current controversies in the management of locally advanced colon cancer

M Gillani, SA Rosen - The American Surgeon™, 2023 - journals.sagepub.com
Colon cancer is a leading cause of cancer-related mortality worldwide, with an estimated
106,180 new cases in 2022. 1 Locally advanced colon cancer (LACC) is particularly …