Evaluating the mechanistic evidence and key data gaps in assessing the potential carcinogenicity of carbon nanotubes and nanofibers in humans

ED Kuempel, MC Jaurand, P Møller… - Critical reviews in …, 2017 - Taylor & Francis
In an evaluation of carbon nanotubes (CNTs) for the IARC Monograph 111, the Mechanisms
Subgroup was tasked with assessing the strength of evidence on the potential …

[HTML][HTML] Polychlorinated Biphenyl (PCB) carcinogenicity with special emphasis on airborne PCBs

LW Robertson, G Ludewig - … /Herausgeber, BIA und KRdL im VDI …, 2011 - ncbi.nlm.nih.gov
Polychlorinated biphenyls (PCBs) are industrial chemicals used in various applications
requiring chemical stabilityand have now become widely dispersed. Their characteristics of …

Uptake and translocation of lesser-chlorinated polychlorinated biphenyls (PCBs) in whole hybrid poplar plants after hydroponic exposure

J Liu, JL Schnoor - Chemosphere, 2008 - Elsevier
Mono-, di-, tri-, and tetra-chlorinated polychlorinated biphenyls (PCBs) are congeners with
greater volatility which remain in air, soils and sediments requiring treatment. In this study …

Exposure to and health effects of volatile PCBs

DO Carpenter - Reviews on environmental health, 2015 - degruyter.com
Abstract Introduction: Polychlorinated biphenyls (PCBs) are persistent, lipophilic
contaminants that are known to increase risk of a number of human diseases. Although …

Identification of sulfated metabolites of 4-chlorobiphenyl (PCB3) in the serum and urine of male rats

K Dhakal, X He, HJ Lehmler, LM Teesch… - Chemical research in …, 2012 - ACS Publications
Polychlorinated biphenyls (PCBs) are legacy pollutants that exert toxicities through various
mechanisms. In recent years exposure to PCBs via inhalation has been recognized as a …

Transgenic rat models for mutagenesis and carcinogenesis

T Nohmi, K Masumura, N Toyoda-Hokaiwado - Genes and Environment, 2017 - Springer
Rats are a standard experimental animal for cancer bioassay and toxicological research for
chemicals. Although the genetic analyses were behind mice, rats have been more frequently …

Protective effect of ginger (Zingiber officinale) against PCB-induced acute hepatotoxicity in male rats

K Ahd, S Dhibi, S Akermi, H Bouzenna, N Samout… - RSC …, 2019 - pubs.rsc.org
After absorption by the organism, polychlorinated biphenyls (PCBs) cross cellular
membranes and pass into blood vessels and the lymphatic system. It is generally in the liver …

Enantioselective transport and biotransformation of chiral hydroxylated metabolites of polychlorinated biphenyls in whole poplar plants

G Zhai, SM Gutowski, HJ Lehmler… - Environmental science & …, 2014 - ACS Publications
Hydroxylated metabolites of polychlorinated biphenyls (OH-PCBs) have been found to be
ubiquitous in the environment due to the oxidative metabolism of their parent PCBs. With …

Hydroxylated metabolites of 4-monochlorobiphenyl and its metabolic pathway in whole poplar plants

G Zhai, HJ Lehmler, JL Schnoor - Environmental science & …, 2010 - ACS Publications
4-Monochlorobiphenyl (CB3), mainly an airborne pollutant, undergoes rapid
biotransformation to produce hydroxylated metabolites (OH− CB3s). However, up to now …

Investigation of mechanism (s) of DNA damage induced by 4-monochlorobiphenyl (PCB3) metabolites

W Xie, K Wang, LW Robertson, G Ludewig - Environment international, 2010 - Elsevier
4-Monochlorobiphenyl (PCB3) is readily converted by xenobiotic-metabolizing enzymes to
dihydroxy-metabolites and quinones. The PCB3 hydroquinone (PCB3-HQ; 2-(4 …