Triage of HPV positive women in cervical cancer screening

N Wentzensen, M Schiffman, T Palmer… - Journal of Clinical …, 2016 - Elsevier
Despite HPV vaccines, screening will remain central for decades to control cervical cancer.
Recently, HPV testing alone or with cytology was introduced as an alternative to cytology …

Association between cervical microbiota and HPV: could this be the key to complete cervical cancer eradication?

E Cascardi, G Cazzato, A Daniele, E Silvestris… - Biology, 2022 - mdpi.com
Simple Summary The microbiota can modulate immune responses and modify the
physiology of the human organism, thereby increasing infective risks and a neoplastic …

Accuracy and efficiency of deep-learning–based automation of dual stain cytology in cervical cancer screening

N Wentzensen, B Lahrmann, MA Clarke… - JNCI: Journal of the …, 2021 - academic.oup.com
Background With the advent of primary human papillomavirus testing followed by cytology
for cervical cancer screening, visual interpretation of cytology slides remains the last …

Screening for cervical cancer precursors with p16/Ki-67 dual-stained cytology: results of the PALMS study

H Ikenberg, C Bergeron, D Schmidt… - Journal of the …, 2013 - academic.oup.com
Background Pap cytology is known to be more specific but less sensitive than testing for
human papillomavirus (HPV) for the detection of high-grade cervical intraepithelial …

Human papillomavirus laboratory testing: the changing paradigm

EM Burd - Clinical microbiology reviews, 2016 - Am Soc Microbiol
High-risk human papillomaviruses (HPVs) cause essentially all cervical cancers, most anal
and oropharyngeal cancers, and some vaginal, vulvar, and penile cancers. Improved …

Microbiome-derived cobalamin and succinyl-CoA as biomarkers for improved screening of anal cancer

S Serrano-Villar, C Tincati, SC Raju, JS Sáenz… - Nature Medicine, 2023 - nature.com
Human papillomavirus can cause preinvasive, high-grade squamous intraepithelial lesions
(HSILs) as precursors to cancer in the anogenital area, and the microbiome is suggested to …

Clinical evaluation of human papillomavirus screening with p16/Ki-67 dual stain triage in a large organized cervical cancer screening program

N Wentzensen, MA Clarke, R Bremer… - JAMA internal …, 2019 - jamanetwork.com
Importance As cervical cancer screening transitions from Papanicolaou cytologic screening
to primary human papillomavirus (HPV) testing worldwide, effective triage tests are needed …

Five-year risk of cervical precancer following p16/Ki-67 dual-stain triage of HPV-positive women

MA Clarke, LC Cheung, PE Castle, M Schiffman… - JAMA …, 2019 - jamanetwork.com
Importance As cervical cancer screening transitions to primary human papillomavirus (HPV)
testing, effective triage and management of HPV-positive women is critical to avoid …

Cervical cancer screening postpandemic: self-sampling opportunities to accelerate the elimination of cervical cancer

T Lozar, R Nagvekar, C Rohrer… - … Journal of Women's …, 2021 - Taylor & Francis
The persisting burden of cervical cancer in underserved populations and low-resource
regions worldwide, worsened by the onset of the COVID-19 pandemic, requires proactive …

p16/Ki-67 dual stain cytology for detection of cervical precancer in HPV-positive women

N Wentzensen, B Fetterman, PE Castle… - Journal of the …, 2015 - academic.oup.com
Abstract Background: Human papillomavirus (HPV)–based cervical cancer screening
requires triage markers to decide who should be referred to colposcopy. p16/Ki-67 dual …