Origins of lifetime health around the time of conception: causes and consequences

TP Fleming, AJ Watkins, MA Velazquez, JC Mathers… - The Lancet, 2018 - thelancet.com
Parental environmental factors, including diet, body composition, metabolism, and stress,
affect the health and chronic disease risk of people throughout their lives, as captured in the …

Optimizing prepregnancy cardiovascular health to improve outcomes in pregnant and postpartum individuals and offspring: a scientific statement from the American …

SS Khan, LPC Brewer, MM Canobbio, MJ Cipolla… - Circulation, 2023 - Am Heart Assoc
This scientific statement summarizes the available preclinical, epidemiological, and clinical
trial evidence that supports the contributions of prepregnancy (and interpregnancy) …

Obesity induces ovarian inflammation and reduces oocyte quality

AP Snider, JR Wood - Reproduction, 2019 - rep.bioscientifica.com
In the United States, 36.5% of women between the ages of 20 and 39 years are obese. This
obesity results in not only metabolic disorders including type II diabetes and cardiovascular …

Nutrition and female fertility: an interdependent correlation

E Silvestris, D Lovero, R Palmirotta - Frontiers in endocrinology, 2019 - frontiersin.org
Besides aging, a number of non-modifiable lifestyle-related factors, such as smoking,
elevated consumption of caffeine and alcohol, stress, agonist sports, chronic exposure to …

Lipids and oocyte developmental competence: the role of fatty acids and β-oxidation

KR Dunning, DL Russell, RL Robker - Reproduction, 2014 - research.monash.edu
Metabolism and ATP levels within the oocyte and adjacent cumulus cells are associated
with quality of oocyte and optimal development of a healthy embryo. Lipid metabolism …

Beyond apoptosis: evidence of other regulated cell death pathways in the ovary throughout development and life

JM Stringer, LR Alesi, AL Winship… - Human Reproduction …, 2023 - academic.oup.com
BACKGROUND Regulated cell death is a fundamental component of numerous
physiological processes; spanning from organogenesis in utero, to normal cell turnover …

Lipid metabolism and endometrial receptivity

T Yang, J Zhao, F Liu, Y Li - Human Reproduction Update, 2022 - academic.oup.com
BACKGROUND Obesity has now been recognized as a high-risk factor for reproductive
health. Although remarkable advancements have been made in ART, a considerable …

Physiological aspects of female fertility: role of the environment, modern lifestyle, and genetics

RJ Hart - Physiological reviews, 2016 - journals.physiology.org
Across the Western World there is an increasing trend to postpone childbearing.
Consequently, the negative influence of age on oocyte quality may lead to a difficulty in …

[HTML][HTML] Excessive oxidative stress in cumulus granulosa cells induced cell senescence contributes to endometriosis-associated infertility

X Lin, Y Dai, X Tong, W Xu, Q Huang, X Jin, C Li… - Redox biology, 2020 - Elsevier
Endometriosis an important cause of female infertility and seriously impact physical and
psychological health of patients. Endometriosis is now considered to be a public health …

Maternal low-grade chronic inflammation and intrauterine programming of health and disease

F Parisi, R Milazzo, VM Savasi, I Cetin - International journal of molecular …, 2021 - mdpi.com
Overweight and obesity during pregnancy have been associated with increased birth
weight, childhood obesity, and noncommunicable diseases in the offspring, leading to a …