Cerebral dopamine neurotrophic factor (CDNF) is an endogenous protein in humans and
other vertebrates, and it has been shown to have protective and restorative effects on cells in …

Parkinson's disease (PD) is a progressive neurodegenerative disease characterized by
gradual loss of midbrain dopamine neurons, leading to impaired motor function. Preclinical …

Cerebral dopamine neurotrophic factor (CDNF) is an unconventional neurotropic factor that
modulates unfolded protein response (UPR) pathway signaling and alleviates endoplasmic …

Cerebral reperfusion injury in stroke, stemming from interconnected thrombotic and
inflammatory signatures, often involves platelet activation, aggregation and its interaction …

Cerebral dopamine neurotrophic factor (CDNF) is an unconventional neurotrophic factor that
is a disease-modifying drug candidate for Parkinson's disease. CDNF has pleiotropic …

Cerebral dopamine neurotrophic factor (CDNF) and its close structural relative,
mesencephalic astrocyte-derived neurotrophic factor (MANF), are proteins with neurotrophic …

Ischaemic stroke causes neuron loss and long-term functional deficits. Unfortunately,
effective approaches to preserving neurons and promoting functional recovery remain …

The discovery of the neurotrophins and their potent survival and trophic effects led to great
enthusiasm about their therapeutic potential to rescue dying neurons in neurodegenerative …

Increasing evidence suggests an essential function for autophagy in unconventional protein
secretion (UPS). However, despite its relevance for the secretion of aggregate-prone …

Recent advancements in brain stimulation and nanomedicine have ushered in a new era of
therapeutic interventions for psychiatric and neurodegenerative disorders. This review …