Controlling allosteric networks in proteins
NV Dokholyan - Chemical reviews, 2016 - ACS Publications
Allosteric transition, defined as conformational changes induced by ligand binding, is one of
the fundamental properties of proteins. Allostery has been observed and characterized in …
the fundamental properties of proteins. Allostery has been observed and characterized in …
Advances in RNA 3D structure modeling using experimental data
RNA is a unique bio-macromolecule that can both record genetic information and perform
biological functions in a variety of molecular processes, including transcription, splicing …
biological functions in a variety of molecular processes, including transcription, splicing …
The HDOCK server for integrated protein–protein docking
Abstract The HDOCK server (http://hdock. phys. hust. edu. cn/) is a highly integrated suite of
homology search, template-based modeling, structure prediction, macromolecular docking …
homology search, template-based modeling, structure prediction, macromolecular docking …
trRosettaRNA: automated prediction of RNA 3D structure with transformer network
RNA 3D structure prediction is a long-standing challenge. Inspired by the recent
breakthrough in protein structure prediction, we developed trRosettaRNA, an automated …
breakthrough in protein structure prediction, we developed trRosettaRNA, an automated …
When will RNA get its AlphaFold moment?
The protein structure prediction problem has been solved for many types of proteins by
AlphaFold. Recently, there has been considerable excitement to build off the success of …
AlphaFold. Recently, there has been considerable excitement to build off the success of …
Structure and degradation of circular RNAs regulate PKR activation in innate immunity
Circular RNAs (circRNAs) produced from back-splicing of exons of pre-mRNAs are widely
expressed, but current understanding of their functions is limited. These RNAs are stable in …
expressed, but current understanding of their functions is limited. These RNAs are stable in …
Integrating end-to-end learning with deep geometrical potentials for ab initio RNA structure prediction
RNAs are fundamental in living cells and perform critical functions determined by their
tertiary architectures. However, accurate modeling of 3D RNA structure remains a …
tertiary architectures. However, accurate modeling of 3D RNA structure remains a …
IL1B increases intestinal tight junction permeability by up-regulation of MIR200C-3p, which degrades occludin mRNA
Background & Aims Defects in the epithelial tight junction (TJ) barrier contribute to
development of intestinal inflammation associated with diseases. Interleukin 1 beta (IL1B) …
development of intestinal inflammation associated with diseases. Interleukin 1 beta (IL1B) …
RNA-Puzzles Round IV: 3D structure predictions of four ribozymes and two aptamers
RNA-Puzzles is a collective endeavor dedicated to the advancement and improvement of
RNA 3D structure prediction. With agreement from crystallographers, the RNA structures are …
RNA 3D structure prediction. With agreement from crystallographers, the RNA structures are …
RNA-Puzzles Round III: 3D RNA structure prediction of five riboswitches and one ribozyme
RNA-Puzzles is a collective experiment in blind 3D RNA structure prediction. We report here
a third round of RNA-Puzzles. Five puzzles, 4, 8, 12, 13, 14, all structures of riboswitch …
a third round of RNA-Puzzles. Five puzzles, 4, 8, 12, 13, 14, all structures of riboswitch …