[HTML][HTML] The emerging role of the piRNA/piwi complex in cancer
Y Liu, M Dou, X Song, Y Dong, S Liu, H Liu, J Tao, W Li… - Molecular cancer, 2019 - Springer
Piwi interacting RNAs (piRNAs) constitute novel small non-coding RNA molecules of
approximately 24–31 nucleotides in length that often bind to members of the piwi protein …
approximately 24–31 nucleotides in length that often bind to members of the piwi protein …
[HTML][HTML] Role of non-coding RNAs and RNA modifiers in cancer therapy resistance
X Zhang, K Xie, H Zhou, Y Wu, C Li, Y Liu, Z Liu, Q Xu… - Molecular cancer, 2020 - Springer
As the standard treatments for cancer, chemotherapy and radiotherapy have been widely
applied to clinical practice worldwide. However, the resistance to cancer therapies is a major …
applied to clinical practice worldwide. However, the resistance to cancer therapies is a major …
[HTML][HTML] Non-coding RNA in cancer drug resistance: Underlying mechanisms and clinical applications
X Zhou, X Ao, Z Jia, Y Li, S Kuang, C Du… - Frontiers in …, 2022 - frontiersin.org
Cancer is one of the most frequently diagnosed malignant diseases worldwide, posing a
serious, long-term threat to patients' health and life. Systemic chemotherapy remains the first …
serious, long-term threat to patients' health and life. Systemic chemotherapy remains the first …
[HTML][HTML] Senescent neutrophils-derived exosomal piRNA-17560 promotes chemoresistance and EMT of breast cancer via FTO-mediated m6A demethylation
B Ou, Y Liu, Z Gao, J Xu, Y Yan, Y Li, J Zhang - Cell death & disease, 2022 - nature.com
Cellular senescence is characterized by a tumor-suppressive program as well as a pro-
inflammatory secretome. Neutrophils constitute significant compositions of malignancies and …
inflammatory secretome. Neutrophils constitute significant compositions of malignancies and …
[HTML][HTML] Pseudogene-derived lncRNAs and their miRNA sponging mechanism in human cancer
W Lou, B Ding, P Fu - Frontiers in cell and developmental biology, 2020 - frontiersin.org
Pseudogenes, abundant in the human genome, are traditionally considered as non-
functional “junk genes.” However, recent studies have revealed that pseudogenes act as key …
functional “junk genes.” However, recent studies have revealed that pseudogenes act as key …
[HTML][HTML] Roles of piRNAs in transposon and pseudogene regulation of germline mRNAs and lncRNAs
C Wang, H Lin - Genome Biology, 2021 - Springer
PIWI proteins, a subfamily of PAZ/PIWI Domain family RNA-binding proteins, are best known
for their function in silencing transposons and germline development by partnering with …
for their function in silencing transposons and germline development by partnering with …
[HTML][HTML] The biogenesis and functions of piRNAs in human diseases
X Wu, Y Pan, Y Fang, J Zhang, M Xie, F Yang… - … Therapy-Nucleic Acids, 2020 - cell.com
Piwi-interacting RNAs (piRNAs) are a novel type of small noncoding RNAs, which are 26–30
nt in length and bind to Piwi proteins. These short RNAs were originally discovered in …
nt in length and bind to Piwi proteins. These short RNAs were originally discovered in …
piRNAs: biogenesis and their potential roles in cancer
B Guo, D Li, L Du, X Zhu - Cancer and Metastasis Reviews, 2020 - Springer
With the length of about 26–31 nt, PIWI-interacting RNA (piRNA) is a small non-coding RNA
(ncRNA) that interacts with PIWI proteins to form the piRNA silencing complex (piRISC). PIWI …
(ncRNA) that interacts with PIWI proteins to form the piRNA silencing complex (piRISC). PIWI …
[HTML][HTML] The biogenesis and biological function of PIWI-interacting RNA in cancer
S Chen, S Ben, J Xin, S Li, R Zheng, H Wang… - Journal of hematology & …, 2021 - Springer
Small non-coding RNAs (ncRNAs) are vital regulators of biological activities, and aberrant
levels of small ncRNAs are commonly found in precancerous lesions and cancer. PIWI …
levels of small ncRNAs are commonly found in precancerous lesions and cancer. PIWI …
Disorders and roles of tsRNA, snoRNA, snRNA and piRNA in cancer
L Xiao, J Wang, S Ju, M Cui, R Jing - Journal of Medical Genetics, 2022 - jmg.bmj.com
Most small non-coding RNAs (sncRNAs) with regulatory functions are encoded by majority
sequences in the human genome, and the emergence of high-throughput sequencing …
sequences in the human genome, and the emergence of high-throughput sequencing …