Mitogen-activated protein kinase: conservation of a three-kinase module from yeast to human
Widmann, Christian, Spencer Gibson, Matthew B. Jarpe, and Gary L. Johnson. Mitogen-
Activated Protein Kinase: Conservation of a Three-Kinase Module From Yeast to Human …
Activated Protein Kinase: Conservation of a Three-Kinase Module From Yeast to Human …
TNF signaling inhibition in the CNS: implications for normal brain function and neurodegenerative disease
MK McCoy, MG Tansey - Journal of neuroinflammation, 2008 - Springer
The role of tumor necrosis factor (TNF) as an immune mediator has long been appreciated
but its function in the brain is still unclear. TNF receptor 1 (TNFR1) is expressed in most cell …
but its function in the brain is still unclear. TNF receptor 1 (TNFR1) is expressed in most cell …
RAF-like protein kinases mediate a deeply conserved, rapid auxin response
The plant-signaling molecule auxin triggers fast and slow cellular responses across land
plants and algae. The nuclear auxin pathway mediates gene expression and controls …
plants and algae. The nuclear auxin pathway mediates gene expression and controls …
Tumor necrosis factor-alpha and the roles it plays in homeostatic and degenerative processes within the central nervous system
SL Montgomery, WJ Bowers - Journal of neuroimmune pharmacology, 2012 - Springer
Abstract Tumor Necrosis Factor-alpha (TNF-α) is a prototypic pro-inflammatory cytokine
involved in the innate immune response. TNF-α ligation and downstream signaling with one …
involved in the innate immune response. TNF-α ligation and downstream signaling with one …
Arterial wall shear stress: observations from the bench to the bedside
JJ Paszkowiak, A Dardik - Vascular and endovascular …, 2003 - journals.sagepub.com
Shear stress is the tangential force of the flowing blood on the endothelial surface of the
blood vessel. Shear is described mathematically for ideal fluids, and in vitro models have …
blood vessel. Shear is described mathematically for ideal fluids, and in vitro models have …
[HTML][HTML] Latent membrane protein 1 of Epstein–Barr virus mimics a constitutively active receptor molecule
Abstract Latent membrane protein 1 (LMP1) of Epstein–Barr virus (EBV) is an integral
membrane protein which has transforming potential and is necessary but not sufficient for B …
membrane protein which has transforming potential and is necessary but not sufficient for B …
Activation, differential localization, and regulation of the stress‐activated protein kinases, extracellular signal–regulated kinase, c‐Jun N‐terminal kinase, and p38 …
G Schett, M Tohidast‐Akrad, JS Smolen… - … : Official Journal of …, 2000 - Wiley Online Library
Objective To investigate whether stress‐and mitogen‐activated protein kinases
(SAPK/MAPK), such as extracellular signal–regulated kinase (ERK), c‐Jun N‐terminal …
(SAPK/MAPK), such as extracellular signal–regulated kinase (ERK), c‐Jun N‐terminal …
Induction of Vascular Endothelial Growth Factor by Hypoxia Is Modulated by a Phosphatidylinositol 3-Kinase/Akt Signaling Pathway in Ha-ras-Transformed Cells …
NM Mazure, EY Chen, KR Laderoute… - Blood, The Journal of …, 1997 - ashpublications.org
Tumor angiogenesis, the development of new blood vessels, is a highly regulated process
that is controlled genetically by alterations in oncogene and tumor suppressor gene …
that is controlled genetically by alterations in oncogene and tumor suppressor gene …
Microglia and macrophages are the major source of tumor necrosis factor in permanent middle cerebral artery occlusion in mice
R Gregersen, K Lambertsen… - Journal of Cerebral …, 2000 - journals.sagepub.com
The proinflammatory cytokine tumor necrosis factor (TNF) is known to be expressed in brain
ischemia; however, its cellular and temporal appearance is not fully settled. In this study …
ischemia; however, its cellular and temporal appearance is not fully settled. In this study …
MAPK/ERK overrides the apoptotic signaling from Fas, TNF, and TRAIL receptors
SEF Tran, TH Holmström, M Ahonen… - Journal of Biological …, 2001 - ASBMB
The tumor necrosis factor (TNF), Fas, and TNF-related apoptosis-inducing ligand (TRAIL)
receptors (R) are highly specific physiological mediators of apoptotic signaling. We …
receptors (R) are highly specific physiological mediators of apoptotic signaling. We …