There is nervous control of the heart by ATP as a cotransmitter in sympathetic,
parasympathetic, and sensory-motor nerves, as well as in intracardiac neurons. Centers in …

Renovascular hypertension is one of the most relevant causes of secondary hypertension,
mostly caused by atherosclerotic renovascular stenosis or fibromuscular dysplasia. The …

The severity of polycystic kidney diseases (PKD) depends on the counterbalancing of
genetic predisposition and environmental factors exerting permissive or protective influence …

To maintain metabolic homeostasis, the body must be able to monitor the concentration of a
large number of substances, including metabolites, in real time and to use that information to …

Extracellular ATP interacts with purinergic type 2 (P2) receptors and elicits many crucial
biological functions. Extracellular ATP is sequentially hydrolyzed to ADP and AMP by the …

Background ATP and derivatives are recognized to be essential agents of paracrine
signaling. It was reported that ATP is an important regulator of the pressure‐natriuresis …

High saturated fat diets have been associated with the development of obesity and
hypertension, along with other pathologies related to the metabolic syndrome. In contrast …

Mineralocorticoid receptor antagonists (MRAs) are a class of anti-hypertensive drugs that act
by blocking aldosterone action. The aim of this study was to evaluate whether the MRAs …

The treatment of hypertension has improved in the last century; attention has been directed
to restoring several altered pathophysiological mechanisms. However, regardless of the …

Objective. Crataeva nurvala is a medicinal plant, which contains a wide range of
polyphenolic and bioactive compounds. The aim of the study was to evaluate the renal …