Although the term “asthma” has been applied to all patients with airway lability and variable
chest symptoms for centuries, phenotypes of asthma with distinct clinical and molecular …

Severe asthma in children is characterized by sustained symptoms despite treatment with
high doses of inhaled corticosteroids or oral corticosteroids. Children with severe asthma …

Severe asthma has a great impact on the quality of life (QOL) of patients and their families.
The magnitude of this morbidity is affected by several personal factors including age …

ABSTRACT OCS play an important role in the management of asthma. However, steroid‐
related AE are common and represent a leading cause of morbidity. Limited published …

Persistent asthma has long been treated with inhaled corticosteroids (CSs), as the mainstay
of therapy. However, their efficacy in patients with more severe disease is limited, which led …

Severe asthma is a heterogeneous and often difficult to treat condition that results in a
disproportionate cost to healthcare systems. Appropriate diagnosis and management of …

Asthma is defined as a chronic inflammatory disorder of the airways which manifests itself as
recurrent episodes of wheezing, breathlessness, chest tightness and cough. It is …

Background Recent trials have assessed the efficacy and safety of novel monoclonal
antibodies such as reslizumab and benralizumab. However, the overall efficacy and safety …

Background Bronchial thermoplasty (BT) is a recently developed treatment for patients with
moderate-to-severe asthma. A few studies have suggested the clinical efficacy of this …

Since the publication, 9 years ago, of the latest SEPAR (Spanish Society of Pulmonology
and Thoracic Surgery) Guidelines on Difficult-to-Control Asthma (DCA), much progress has …