Human testis-expressed (TEX) genes: a review focused on spermatogenesis and male fertility

H Bellil, F Ghieh, E Hermel, B Mandon-Pepin… - Basic and clinical …, 2021 - Springer
Spermatogenesis is a complex process regulated by a multitude of genes. The identification
and characterization of male-germ-cell-specific genes is crucial to understanding the …

Redefining serological diagnostics with immunoaffinity proteomics

J Walter, Z Eludin, AP Drabovich - Clinical Proteomics, 2023 - Springer
Serological diagnostics is generally defined as the detection of specific human
immunoglobulins developed against viral, bacterial, or parasitic diseases. Serological tests …

Semen proteomics of COVID-19 convalescent men reveals disruption of key biological pathways relevant to male reproductive function

S Ghosh, S Parikh, MU Nissa, A Acharjee, A Singh… - ACS …, 2022 - ACS Publications
A considerable section of males suffered from COVID-19, with many experiencing long-term
repercussions. Recovered males have been documented to have compromised fertility …

Research on the human proteome reaches a major milestone:> 90% of predicted human proteins now credibly detected, according to the HUPO Human Proteome …

GS Omenn, L Lane, CM Overall… - Journal of proteome …, 2020 - ACS Publications
According to the 2020 Metrics of the HUPO Human Proteome Project (HPP), expression has
now been detected at the protein level for> 90% of the 19 773 predicted proteins coded in …

Rational design and development of SARS-CoV-2 serological diagnostics by immunoprecipitation-targeted proteomics

Z Fu, Y Rais, D Dara, D Jackson… - Analytical …, 2022 - ACS Publications
Current design of serological tests utilizes conservative immunoassay approaches and is
focused on fast and convenient assay development, throughput, straightforward …

Comparative proteomics analysis of human FFPE testicular tissues reveals new candidate biomarkers for distinction among azoospermia types and subtypes

K Davalieva, A Rusevski, M Velkov, P Noveski… - Journal of …, 2022 - Elsevier
Understanding molecular mechanisms that underpin azoospermia and discovery of
biomarkers that could enable reliable, non-invasive diagnosis are highly needed. Using …

Emerging role of novel seminal plasma bio-markers in Male infertility: a review

N Kumar, NK Singh - European Journal of Obstetrics & Gynecology and …, 2020 - Elsevier
Male infertility has emerged as an important cause of infertility worldwide. There are many
factors affecting male fertility and research is going on to know impact of various factors on …

Mapping isoform abundance and interactome of the endogenous TMPRSS2-ERG fusion protein by orthogonal immunoprecipitation–mass spectrometry assays

Z Fu, Y Rais, TA Bismar, ME Hyndman, XC Le… - Molecular & Cellular …, 2021 - ASBMB
TMPRSS2-ERG gene fusion, a molecular alteration found in nearly half of primary prostate
cancer cases, has been intensively characterized at the transcript level. However limited …

Identification of TEX101-associated Proteins Through Proteomic Measurement of Human Spermatozoa Homozygous for the Missense Variant rs35033974*[S]

C Schiza, D Korbakis, K Jarvi, EP Diamandis… - Molecular & Cellular …, 2019 - ASBMB
TEX101 is a germ-cell-specific protein and a validated biomarker of male infertility. Mouse
TEX101 was found essential for male fertility and was suggested to function as a cell surface …

Mass spectrometry-based proteomics in basic and translational research of SARS-CoV-2 coronavirus and its emerging mutants

Y Rais, Z Fu, AP Drabovich - Clinical Proteomics, 2021 - Springer
Molecular diagnostics of the coronavirus disease of 2019 (COVID-19) now mainly relies on
the measurements of viral RNA by RT-PCR, or detection of anti-viral antibodies by …