LATE‐NC in Alzheimer's disease: Molecular aspects and synergies
Alzheimer's disease (AD) is classically characterized by senile plaques and neurofibrillary
tangles (NFTs). However, multiple copathologies can be observed in the AD brain and …
tangles (NFTs). However, multiple copathologies can be observed in the AD brain and …
Cryptic splicing of stathmin-2 and UNC13A mRNAs is a pathological hallmark of TDP-43-associated Alzheimer's disease
Nuclear clearance and cytoplasmic accumulations of the RNA-binding protein TDP-43 are
pathological hallmarks in almost all patients with amyotrophic lateral sclerosis (ALS) and up …
pathological hallmarks in almost all patients with amyotrophic lateral sclerosis (ALS) and up …
[HTML][HTML] Prion-like Spreading of Disease in TDP-43 Proteinopathies
TDP-43 is a ubiquitous nuclear protein that plays a central role in neurodegenerative
disorders collectively known as TDP-43 proteinopathies. Under physiological conditions …
disorders collectively known as TDP-43 proteinopathies. Under physiological conditions …
Clinical criteria for a limbic-predominant amnestic neurodegenerative syndrome
N Corriveau-Lecavalier, H Botha… - Brain …, 2024 - academic.oup.com
Predominant limbic degeneration has been associated with various underlying aetiologies
and an older age, predominant impairment of episodic memory and slow clinical …
and an older age, predominant impairment of episodic memory and slow clinical …
[HTML][HTML] A limbic-predominant amnestic neurodegenerative syndrome associated with TDP-43 pathology
N Corriveau-Lecavalier, H Botha, J Graff-Radford… - MedRxiv, 2023 - ncbi.nlm.nih.gov
Limbic-predominant age-related TDP-43 encephalopathy (LATE) is a neuropathologically-
defined disease that affects 40% of persons in advanced age, but its associated …
defined disease that affects 40% of persons in advanced age, but its associated …
Novel CSF biomarkers tracking autoimmune inflammatory and neurodegenerative aspects of CNS diseases
E Kapaki, AG Vakrakou, F Boufidou - Diagnostics, 2022 - mdpi.com
The accurate diagnosis of neuroinflammatory (NIDs) and neurodegenerative (NDDs)
diseases and the stratification of patients into disease subgroups with distinct disease …
diseases and the stratification of patients into disease subgroups with distinct disease …
[HTML][HTML] Cerebrospinal Fluid Classical Biomarker Levels in Mixed vs. Pure A+T+ (A+T1+) Alzheimer's Disease
I Tsantzali, A Athanasaki, F Boufidou… - Biomedicines, 2024 - mdpi.com
Background: Alzheimer's disease (AD) may present with pure (typical or atypical) and mixed
phenotypes, sometimes causing difficulties in (differential) diagnosis. In order to achieve a …
phenotypes, sometimes causing difficulties in (differential) diagnosis. In order to achieve a …