Proteostasis of islet amyloid polypeptide: a molecular perspective of risk factors and protective strategies for type II diabetes

D Milardi, E Gazit, SE Radford, Y Xu… - Chemical …, 2021 - ACS Publications
The possible link between hIAPP accumulation and β-cell death in diabetic patients has
inspired numerous studies focusing on amyloid structures and aggregation pathways of this …

Development of multifunctional molecules as potential therapeutic candidates for Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis in the …

MG Savelieff, G Nam, J Kang, HJ Lee, M Lee… - Chemical …, 2018 - ACS Publications
Neurodegenerative diseases pose a substantial socioeconomic burden on society.
Unfortunately, the aging world population and lack of effective cures foreshadow a negative …

Flavonoids as prospective neuroprotectants and their therapeutic propensity in aging associated neurological disorders

M Ayaz, A Sadiq, M Junaid, F Ullah, M Ovais… - Frontiers in aging …, 2019 - frontiersin.org
Modern research has revealed that dietary consumption of flavonoids and flavonoids-rich
foods significantly improve cognitive capabilities, inhibit or delay the senescence process …

Oxidative stress in alzheimer's disease: A review on emergent natural polyphenolic therapeutics

L Cassidy, F Fernandez, JB Johnson, M Naiker… - … therapies in medicine, 2020 - Elsevier
Objectives The aim of this research was to review the literature on Alzheimer's disease (AD)
with a focus on polyphenolics as antioxidant therapeutics. Design This review included a …

The neuroprotective potentiality of flavonoids on Alzheimer's disease

A Calderaro, GT Patanè, E Tellone, D Barreca… - International journal of …, 2022 - mdpi.com
Alzheimer's disease (AD), due to its spread, has become a global health priority, and is
characterized by senile dementia and progressive disability. The main cause of AD and …

Management of oxidative stress and other pathologies in Alzheimer's disease

M Simunkova, SH Alwasel, IM Alhazza, K Jomova… - Archives of …, 2019 - Springer
Alzheimer's disease (AD) is a multifactorial neurodegenerative disorder, characterized by
the formation, aggregation and accumulation of amyloid beta, perturbed metal (copper, iron …

A minireview of quercetin: from its metabolism to possible mechanisms of its biological activities

HG Ulusoy, N Sanlier - Critical Reviews in Food Science and …, 2020 - Taylor & Francis
Quercetin, one of the most taken flavonoid with diet, belongs to the family of flavonols in
which kaempferol and myricetin are also found. Quercetin occurs as a glycoside (with linked …

Polyphenols from food and natural products: Neuroprotection and safety

RFM Silva, L Pogačnik - Antioxidants, 2020 - mdpi.com
Polyphenols are naturally occurring micronutrients that are present in many food sources.
Besides being potent antioxidants, these molecules may also possess anti-inflammatory …

Neuropharmacological effects of quercetin: a literature-based review

MS Islam, C Quispe, R Hossain, MT Islam… - Frontiers in …, 2021 - frontiersin.org
Quercetin (QUR) is a natural bioactive flavonoid that has been lately very studied for its
beneficial properties in many pathologies. Its neuroprotective effects have been …

Myricetin: A dietary molecule with diverse biological activities

DK Semwal, RB Semwal, S Combrinck, A Viljoen - Nutrients, 2016 - mdpi.com
Myricetin is a common plant-derived flavonoid and is well recognised for its nutraceuticals
value. It is one of the key ingredients of various foods and beverages. The compound …