Immunogenetics of Hashimoto's thyroiditis

DA Chistiakov - Journal of autoimmune diseases, 2005 - Springer
Hashimoto's thyroiditis (HT) is an organ-specific T-cell mediated disease. It is a complex
disease, with a strong genetic component. To date, significant progress has been made …

Autoimmune thyroid disease

N Stathatos, GH Daniels - Current opinion in rheumatology, 2012 - journals.lww.com
Autoimmune thyroid disease : Current Opinion in Rheumatology Autoimmune thyroid disease :
Current Opinion in Rheumatology Log in or Register Subscribe to journalSubscribe Get new …

Variants near FOXE1 are associated with hypothyroidism and other thyroid conditions: using electronic medical records for genome-and phenome-wide studies

JC Denny, DC Crawford, MD Ritchie… - The American Journal of …, 2011 - cell.com
We repurposed existing genotypes in DNA biobanks across the Electronic Medical Records
and Genomics network to perform a genome-wide association study for primary …

Possible association between thyroid autoimmunity and Meniere's disease

B Fattori, A Nacci, A Dardano, I Dallan… - Clinical & …, 2008 - academic.oup.com
Various aetiopathological mechanisms have been postulated to be at the root of Menière's
disease (MD), and some data suggest that there may be also an underlying autoimmune …

[PDF][PDF] Thyroperoxidase, thyroglobulin, Na (+)/I (-) symporter, pendrin in thyroid autoimmunity

B Czarnocka - Front Biosci, 2011 - article.imrpress.com
The autoimmune thyroid diseases (AITD), Graves' disease (GD) and Hashimoto's thyroiditis
(HT) are most common endocrine disorders in humans. Both disorders are characterized by …

Pendrin is a novel autoantigen recognized by patients with autoimmune thyroid diseases

A Yoshida, I Hisatome, S Taniguchi… - The Journal of …, 2009 - academic.oup.com
Context: Pendrin is an apical protein of thyroid follicular cells, responsible for the efflux of
iodide into the follicular lumen via an iodide-chloride transport mechanism. It is unknown …

Genetic investigation of FOXE1 polyalanine tract in thyroid diseases: new insight on the role of FOXE1 in thyroid carcinoma

R Kallel, S Belguith-Maalej, A Akdi, M Mnif… - Cancer …, 2011 - content.iospress.com
FOXE1 polyalanine tract (poly-Ala) has been associated with thyroid dysgenesis. Recently,
the SNP (rs1867277:-238G> A) within the FOXE1 5'UTR was involved in the genetic …

[HTML][HTML] Utility of antibodies in the diagnoses of thyroid diseases: a review article

AK Gupta, S Kumar - Cureus, 2022 - ncbi.nlm.nih.gov
Thyroid problems are among the most widespread endocrine illnesses, affecting individuals
in India and the global population. A thyroid function test is used to diagnose, screen, and …

Genome-wide linkage analysis reveals evidence for four new susceptibility loci for familial euthyroid goiter

Y Bayer, S Neumann, B Meyer… - The Journal of …, 2004 - academic.oup.com
Euthyroid goiter is characterized by diffuse or nodular enlargement of the thyroid gland.
Iodine deficiency and cigarette smoking have been identified as important environmental …

Overexpression of Interleukin-4 in the Thyroid of Transgenic Mice Upregulates the Expression of Duox1 and the Anion Transporter Pendrin

Z Eskalli, Y Achouri, S Hahn, MC Many, J Craps… - Thyroid, 2016 - liebertpub.com
Background: The dual oxidases (Duox) are involved in hydrogen peroxide generation,
which is essential for thyroid hormone synthesis, and therefore they are markers of thyroid …