Oxidative stress modulating nanomaterials and their biochemical roles in nanomedicine

KD Patel, Z Keskin-Erdogan, P Sawadkar… - Nanoscale …, 2024 - pubs.rsc.org
Many pathological conditions are predominantly associated with oxidative stress, arising
from reactive oxygen species (ROS); therefore, the modulation of redox activities has been a …

Novel Methods and Approaches for Safety Evaluation of Nanoparticle Formulations: A Focus Towards In Vitro Models and Adverse Outcome Pathways

MG Tirumala, P Anchi, S Raja, M Rachamalla… - Frontiers in …, 2021 - frontiersin.org
Nanotoxicology is an emerging field employed in the assessment of unintentional
hazardous effects produced by nanoparticles (NPs) impacting human health and the …

Guidance on risk assessment of nanomaterials to be applied in the food and feed chain: Human and animal health

EFSA Scientific Committee, S More, V Bampidis… - Efsa …, 2021 - Wiley Online Library
The EFSA has updated the Guidance on risk assessment of the application of nanoscience
and nanotechnologies in the food and feed chain, human and animal health. It covers the …

Guidance on risk assessment of nanomaterials to be applied in the food and feed chain: human and animal health

EFSA Scientific Committee - EFSA Journal, 2021 - orbit.dtu.dk
The EFSA has updated the Guidance on risk assessment of the application of nanoscience
and nanotechnologies in the food and feed chain, human and animal health. It covers the …

The comet assay: ready for 30 more years

P Møller - Mutagenesis, 2018 - academic.oup.com
During the last 30 years, the comet assay has become widely used for the measurement of
DNA damage and repair in cells and tissues. A landmark achievement was reached in 2016 …

Precision nanotoxicology in drug development: Current trends and challenges in safety and toxicity implications of customized multifunctional nanocarriers for drug …

A Ahmad, M Imran, N Sharma - Pharmaceutics, 2022 - mdpi.com
The dire need for the assessment of human and environmental endangerments of
nanoparticulate material has motivated the formulation of novel scientific tools and …

Redox-active nanomaterials for nanomedicine applications

CM Sims, SK Hanna, DA Heller, CP Horoszko… - Nanoscale, 2017 - pubs.rsc.org
Nanomedicine utilizes the remarkable properties of nanomaterials for the diagnosis,
treatment, and prevention of disease. Many of these nanomaterials have been shown to …

Genotoxicity testing of nanomaterials

R Landsiedel, N Honarvar, SB Seiffert… - Wiley …, 2022 - Wiley Online Library
Nanomaterials have outstanding and unprecedented advantageous material properties but
may also cause adverse effects in humans upon exposure. Testing nanomaterials for …

Genotoxicity assessment of nanomaterials: recommendations on best practices, assays, and methods

R Elespuru, S Pfuhler, MJ Aardema… - Toxicological …, 2018 - academic.oup.com
Nanomaterials (NMs) present unique challenges in safety evaluation. An international
working group, the Genetic Toxicology Technical Committee of the International Life …

Risk assessment and risk minimization in nanomedicine: a need for predictive, alternative, and 3Rs strategies

L Accomasso, C Cristallini, C Giachino - Frontiers in Pharmacology, 2018 - frontiersin.org
The use of nanomaterials in medicine has grown very rapidly, leading to a concern about
possible health risks. Surely, the application of nanotechnology in medicine has many …