Mechanical properties of whole-body soft human tissues: a review

G Singh, A Chanda - Biomedical Materials, 2021 - iopscience.iop.org
The mechanical properties of soft tissues play a key role in studying human injuries and their
mitigation strategies. While such properties are indispensable for computational modelling …

A materials roadmap to functional neural interface design

SM Wellman, JR Eles, KA Ludwig… - Advanced functional …, 2018 - Wiley Online Library
Advancements in neurotechnologies for electrophysiology, neurochemical sensing,
neuromodulation, and optogenetics are revolutionizing scientific understanding of the brain …

Nanoindentation of soft biological materials

L Qian, H Zhao - Micromachines, 2018 - mdpi.com
Nanoindentation techniques, with high spatial resolution and force sensitivity, have recently
been moved into the center of the spotlight for measuring the mechanical properties of …

Region and species dependent mechanical properties of adolescent and young adult brain tissue

DB MacManus, B Pierrat, JG Murphy, MD Gilchrist - Scientific reports, 2017 - nature.com
Traumatic brain injuries, the leading cause of death and disability in children and young
adults, are the result of a rapid acceleration or impact of the head. In recent years, a global …

Brain modelling in the framework of anisotropic hyperelasticity with time fractional damage evolution governed by the Caputo-Almeida fractional derivative

GZ Voyiadjis, W Sumelka - Journal of the mechanical behavior of …, 2019 - Elsevier
In this paper the human brain tissue constitutive model for monotonic loading is developed.
The model in this work is based on the anisotropic hyperelasticity assumption (the …

Tissue‐scale biomechanical testing of brain tissue for the calibration of nonlinear material models

J Faber, J Hinrichsen, A Greiner, N Reiter… - Current …, 2022 - Wiley Online Library
Brain tissue is one of the most complex and softest tissues in the human body. Due to its
ultrasoft and biphasic nature, it is difficult to control the deformation state during …

Protection of cortex by overlying meninges tissue during dynamic indentation of the adolescent brain

DB MacManus, B Pierrat, JG Murphy, MD Gilchrist - Acta biomaterialia, 2017 - Elsevier
Traumatic brain injury (TBI) has become a recent focus of biomedical research with a
growing international effort targeting material characterization of brain tissue and …

Regional characterization of the dynamic mechanical properties of human brain tissue by microindentation

A Menichetti, DB MacManus, MD Gilchrist… - International Journal of …, 2020 - Elsevier
Traumatic brain injury (TBI) is an important cause of mortality and morbidity worldwide. Finite
element models of the human head are used widely to simulate TBI loading scenarios, to …

Glycolytic preconditioning in astrocytes mitigates trauma-induced neurodegeneration

R Solano Fonseca, P Metang, N Egge, Y Liu… - Elife, 2021 - elifesciences.org
Concussion is associated with a myriad of deleterious immediate and long-term
consequences. Yet the molecular mechanisms and genetic targets promoting the selective …

A viscoelastic analysis of the P56 mouse brain under large-deformation dynamic indentation

DB MacManus, B Pierrat, JG Murphy, MD Gilchrist - Acta Biomaterialia, 2017 - Elsevier
The brain is a complex organ made up of many different functional and structural regions
consisting of different types of cells such as neurons and glia, as well as complex anatomical …