Tailoring the nuclear Overhauser effect for the study of small and medium-sized molecules by solvent viscosity manipulation

P Lameiras, JM Nuzillard - Progress in Nuclear Magnetic Resonance …, 2021 - Elsevier
The nuclear Overhauser effect (NOE) is a consequence of cross-relaxation between nuclear
spins mediated by dipolar coupling. Its sensitivity to internuclear distances has made it an …

The immunodominant site of a synthetic immunogen has a conformational preference in water for a type-II reverse turn

H Jane Dyson, KJ Cross, RA Houghten, IA Wilson… - Nature, 1985 - nature.com
Many short synthetic peptides have now been shown to induce antibodies reactive with their
cognate sequences in the intact folded protein1–8. Aside from the usefulness of such …

Stereochemically constrained peptides. Theoretical and experimental studies on the conformations of peptides containing 1-aminocyclohexanecarboxylic acid

PKC Paul, M Sukumar, R Bardi… - journal of the …, 1986 - ACS Publications
Conformational energy calculations on the model system VV-acetyl-l-
aminocyclohexanecarboxylic acid TV'-methylamide (Ac-Acc6-NHMe), using an average …

Theoretical and practical aspects of one-and two-dimensional heteronuclear Overhauser experiments and selective 13C T1-determinations of heteronuclear distances

KE Kövér, G Batta - Progress in nuclear magnetic resonance spectroscopy, 1987 - Elsevier
2.2. Spectral densities and frequency dependence 2.3. Effects of internal reorientation,
equivalent nuclei, cross-correlations. strong couplings and multispin terms on steady-state …

Delineation of Conformational Preferences in Human Salivary Statherin by 1H, 31P NMR and CD Studies: Sequential Assignment and Structure-Function …

GA Naganagowda, TL Gururaja… - Journal of Biomolecular …, 1998 - Taylor & Francis
Membrane—induced solution structure of human salivary statherin, a 43 amino acid residue
acidic phosphoprotein, has been investigated by two—dimensional proton nuclear magnetic …

A new approach to receptor ligand design: synthesis and conformation of a new class of potent and highly selective μ opioid antagonists utilizing …

W Kazmierski, VJ Hruby - Tetrahedron, 1988 - Elsevier
Investigations of the physiological functions of opioid receptors (μ, δ, κ and others) require
potent and selective receptor ligands. Conformational constraint provides a useful approach …

Terminal effect of chiral residue on helical screw sense in achiral peptides

Y Inai, Y Kurokawa… - … : Original Research on …, 1999 - Wiley Online Library
To understand the terminal effect of chiral residue for determining a helical screw sense, we
adopted five kinds of peptides I–V containing N‐and/or C‐terminal chiral Leu residue (s) …

Delineation of an Active Fragment and Poly(l-proline) II Conformation for Candidacidal Activity of Bactenecin 5

PA Raj, E Marcus, M Edgerton - Biochemistry, 1996 - ACS Publications
Bactenecin 5 and its fragments [BN22 (1− 22), BN16 (7− 22), and BC24 (20− 43)] were
synthesized by solid-phase methods. Their antifungal activities on Candida albicans have …

Method of determining protein conformations by the two-dimensional nuclear Overhauser enhancement spectroscopy data

SA Sherman, AM Andrianov… - Journal of Biomolecular …, 1987 - Taylor & Francis
A method is suggested to determine the most probable values of the angles Φ, Ψ of the
protein backbone by the data on the availability and absence of d connectivities in the two …

Effects of N-Terminal L-Amino Acid Residues on Helical Screw Sense in Achiral Peptides.

Y Inai, Y Kurokawa, A Ida, T Hirabayashi - Bulletin of the Chemical …, 1999 - jlc.jst.go.jp
To understand the effects of N-terminal L-residues on dominating helical screw sense in
achiral peptides, we adopted six kinds of peptides Boc–X–(Aib–ΔPhe) 2–Aib–OMe (Boc, t …