Safety and efficacy of intravenous iron therapy in reducing requirement for allogeneic blood transfusion: systematic review and meta-analysis of randomised clinical …

E Litton, J Xiao, KM Ho - Bmj, 2013 - bmj.com
Objectives To evaluate the efficacy and safety of intravenous iron, focusing primarily on its
effects on haemoglobin, requirement for transfusion, and risk of infection. Design Systematic …

Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases

DB Kell - BMC medical genomics, 2009 - Springer
Background The production of peroxide and superoxide is an inevitable consequence of
aerobic metabolism, and while these particular'reactive oxygen species'(ROSs) can exhibit a …

Guidelines on the management of anaemia and red cell transfusion in adult critically ill patients.

A Retter, D Wyncoll, R Pearse… - British journal of …, 2013 - search.ebscohost.com
The article offers information on the management of anaemia and red cell transfusion in
adult critically ill patients. It states that erythropoietin should not be used to treat anaemia in …

Iron-based superparamagnetic nanoparticle contrast agents for MRI of infection and inflammation

A Neuwelt, N Sidhu, CAA Hu, G Mlady… - American Journal of …, 2015 - Am Roentgen Ray Soc
OBJECTIVE. In this article, we summarize the progress to date on the use of
superparamagnetic iron oxide nanoparticles (SPIONs) as contrast agents for MRI of …

Targeting the hepcidin–ferroportin axis to develop new treatment strategies for anemia of chronic disease and anemia of inflammation

CC Sun, V Vaja, JL Babitt, HY Lin - American journal of …, 2012 - Wiley Online Library
Anemia of chronic disease (ACD) or anemia of inflammation is prevalent in patients with
chronic infection, autoimmune disease, cancer, and chronic kidney disease. ACD is …

Nutrition in inflammatory bowel disease

P Schreiner, M Martinho-Grueber, D Studerus… - Digestion, 2020 - karger.com
Background: Westernization, above all associated changes in diet, has been postulated to
be one of the most important factors contributing to the increasing incidence in inflammatory …

Infection risk with bolus versus maintenance iron supplementation in hemodialysis patients

MA Brookhart, JK Freburger, AR Ellis… - Journal of the …, 2013 - journals.lww.com
Intravenous iron may promote bacterial growth and impair host defense, but the risk of
infection associated with iron supplementation is not well defined. We conducted a …

Anemia of chronic disease: a unique defect of iron recycling for many different chronic diseases

E Poggiali, MM De Amicis, I Motta - European journal of internal medicine, 2014 - Elsevier
Anemia of chronic disease (ACD) is frequently observed in patients with chronic diseases as
a significant contributor to morbidity and mortality, which can aggravate the severity of …

A randomized, open-label trial of iron isomaltoside 1000 (Monofer®) compared with iron sucrose (Venofer®) as maintenance therapy in haemodialysis patients

S Bhandari, PA Kalra, J Kothari… - Nephrology Dialysis …, 2015 - academic.oup.com
Background Iron deficiency anaemia is common in patients with chronic kidney disease, and
intravenous iron is the preferred treatment for those on haemodialysis. The aim of this trial …

The treatment of chronic anemia in heart failure: a global approach

VE Bianchi, S von Haehling - Clinical Research in Cardiology, 2023 - Springer
Chronic anemia is an independent risk factor for mortality in patients with heart failure (HF).
Restoring physiological hemoglobin (Hb) levels is essential to increase oxygen transport …