Adaptive Resonance Theory, or ART, is a cognitive and neural theory of how the brain
autonomously learns to categorize, recognize, and predict objects and events in a changing …

As indicated by the profound cognitive impairments caused by cholinergic receptor
antagonists, cholinergic neurotransmission has a vital role in cognitive function, specifically …

Learning and memory are assumed to be supported by mechanisms that involve cholinergic
transmission and hippocampal theta. Using G protein–coupled receptor-activation–based …

Pharmacological data clearly indicate that both muscarinic and nicotinic acetylcholine
receptors have a role in the encoding of new memories. Localized lesions and antagonist …

This review describes the preclinical mechanisms that may underlie the increased
therapeutic benefit of combination therapy—with the N-methyl-d-aspartate receptor …

While non-REM (NREM) sleep has been strongly implicated in the reactivation and
consolidation of memory traces, the role of rapid-eye movement (REM) sleep remains …

Publisher Summary This chapter focuses on how the different physiological effects of
acetylcholine could interact to alter specific functional properties of the cortex …

Age-related neurological disorders (ANDs), including neurodegenerative diseases, are
multifactorial disorders with a risk that increases with aging. ANDs are generally …

Cholinergic septohippocampal projections from the medial septal area to the hippocampus
are proposed to have important roles in cognition by modulating properties of the …

Muscarinic M1 acetylcholine receptors (M1Rs) are highly expressed in the hippocampus,
and their inhibition or ablation disrupts the encoding of spatial memory. It has been …