Significance: During wound healing of the skin, keratinocytes should move over while still
adhering to their underlying matrix. Thus, mechanistic insights into the wound-healing …

During cutaneous wound healing, keratinocyte proliferation and migration are critical for re-
epithelialization. In addition the epidermis secretes growth factors, cytokines, proteases, and …

Significance: Integrins are bidirectional signaling receptors for extracellular matrix that
regulate both inside-out signaling that controls keratinocyte-mediated changes to the wound …

The aim of the study was to assess the propolis effect on fibronectin metabolism in the
course of burn wounds healing process. A model of burn wound healing of pig skin was …

Ganglioside GM3 mediates adipocyte insulin resistance, but the role of GM3 in diabetic
wound healing, a major cause of morbidity, is unclear. The purpose of this study was to …

The local inflammatory environment of the cell promotes the growth of epithelial cancers.
Therefore, controlling inflammation locally using a material in a sustained, non-steroidal …

The migration of keratinocytes in wound healing requires coordinated activities of the motility
machinery of a cell, the cytoskeleton, and matrix adhesions. In this study, we assessed the …

Three major laminin and collagen-binding integrins in skin (α6β4, α3β1, and α2β1) are
involved in keratinocyte adhesion to the dermis and dissemination of skin cells during …

Plakophilin 2 (PKP2), a desmosome component, modulates the activity and localization of
the ce: small-caps GTPase RhoA at sites of cell–cell contact. PKP2 regulates cortical actin …

Wound healing is regulated by a complex, spatiotemporally controlled interplay between
resident and circulating cells, extracellular matrix (ECM), chemical, biochemical …