Anti-NMDA receptor autoimmune encephalitis: diagnosis and management strategies

L Nguyen, C Wang - International journal of general medicine, 2023 - Taylor & Francis
Abstract Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is the most recognized
form of autoimmune encephalitis. It is characterized by a constellation of neurologic and …

Origins and immunopathogenesis of autoimmune central nervous system disorders

S Ramanathan, F Brilot, SR Irani, RC Dale - Nature Reviews Neurology, 2023 - nature.com
The field of autoimmune neurology is rapidly evolving, and recent discoveries have
advanced our understanding of disease aetiologies. In this article, we review the key …

Immunotherapies in MuSK-positive Myasthenia Gravis; an IgG4 antibody-mediated disease

AG Vakrakou, E Karachaliou, E Chroni… - Frontiers in …, 2023 - frontiersin.org
Muscle-specific kinase (MuSK) Myasthenia Gravis (MG) represents a prototypical antibody-
mediated disease characterized by predominantly focal muscle weakness (neck, facial, and …

Antibody therapies in autoimmune encephalitis

I Smets, MJ Titulaer - Neurotherapeutics, 2022 - Springer
Autoimmune encephalitis (AE) comprises a heterogeneous group of disorders in which the
host immune system targets self-antigens expressed in the central nervous system. The …

IgG4 autoantibodies in organ-specific autoimmunopathies: reviewing class switching, antibody-producing cells, and specific immunotherapies

I Koneczny, J Tzartos, M Mané-Damas… - Frontiers in …, 2022 - frontiersin.org
Organ-specific autoimmunity is often characterized by autoantibodies targeting proteins
expressed in the affected tissue. A subgroup of autoimmunopathies has recently emerged …

Immunotherapy in autoimmune encephalitis

BP Trewin, I Freeman, S Ramanathan… - Current Opinion in …, 2022 - journals.lww.com
Early first-line immunotherapies, including corticosteroids and plasma exchange, improve
outcomes, with emerging evidence showing second-line immunotherapies (especially …

Distinct movement disorders in contactin-associated-protein-like-2 antibody-associated autoimmune encephalitis

F Gövert, L Abrante, J Becktepe, B Balint, C Ganos… - Brain, 2023 - academic.oup.com
Autoimmune encephalitis can be classified into antibody-defined subtypes, which can
manifest with immunotherapy-responsive movement disorders sometimes mimicking non …

Myelin oligodendrocyte glycoprotein antibody associated cerebral cortical encephalitis: case reports and review of literature

H Shu, M Ding, P Shang, J Song, Y Lang… - Frontiers in Human …, 2022 - frontiersin.org
Myelin oligodendrocyte glycoprotein antibody-associated disease is an immune-mediated
demyelinating disease of the central nervous system that is present in both adults and …

Autoimmune encephalitis in children

D Hardy - Pediatric Neurology, 2022 - Elsevier
Autoimmune encephalitis is a group of central nervous system (CNS) inflammatory disorders
that most commonly affect young adults and children. These disorders are closely …

The role of intrathecal free light chains kappa for the detection of autoimmune encephalitis in subacute onset neuropsychiatric syndromes

D Bertram, T Tsaktanis, A Berthele, T Korn - Scientific Reports, 2023 - nature.com
Intrathecal synthesis of free light chains kappa (FLCK) is increasingly recognized as a
marker of inflammatory CNS pathologies. Here, we tested the performance of FLCK in …