The cytoskeleton is the major mechanical structure of the cell; it is a complex, dynamic
biopolymer network comprising microtubules, actin, and intermediate filaments. Both the …

Techniques of bone reconstructive surgery are largely based on conventional, non-cell-
based therapies that rely on the use of durable materials from outside the patient's body. In …

Through evolution, nature has presented a set of remarkable protein materials, including
elastins, silks, keratins and collagens with superior mechanical performances that play …

Cells sense mechanical signals from their microenvironment and transduce them to the
nucleus to regulate gene expression programs. To elucidate the physical mechanisms …

Integrin‐based mechanotransduction involves a complex focal adhesion (FA)‐associated
machinery that is able to detect and respond to forces exerted either through components of …

The cytoskeleton is generally visualized by light or electron microscopy as a meshwork of
protein filaments that spans the space between the nuclear envelope and the plasma …

Fiber reinforced polymer (FRP) composites are widely used in repairing concrete or wood
structures. However, the long term performance of FRP-bonded systems can be seriously …

Experimental control over progenitor cell lineage specification can be achieved by
modulating properties of the cell's microenvironment. These include physical properties of …

Peripheral somatosensory circuits are known to respond to diverse stimulus modalities. The
energy modalities capable of eliciting somatosensory responses traditionally belong to …

The superior mechanical behavior of carbon nanotubes (CNT) and their electrical and
thermal functionalities has motivated researchers to exploit them as building blocks to …