[HTML][HTML] TNF in human tuberculosis: a double-edged sword

JM Yuk, JK Kim, IS Kim, EK Jo - Immune Network, 2024 - ncbi.nlm.nih.gov
TNF, a pleiotropic proinflammatory cytokine, is important for protective immunity and
immunopathology during Mycobacterium tuberculosis (Mtb) infection, which causes …

Nucleocapsid-specific T cell responses associate with control of SARS-CoV-2 in the upper airways before seroconversion

TM Eser, O Baranov, M Huth, MIM Ahmed… - Nature …, 2023 - nature.com
Despite intensive research since the emergence of SARS-CoV-2, it has remained unclear
precisely which components of the early immune response protect against the development …

Atg8ylation as a host-protective mechanism against Mycobacterium tuberculosis

V Deretic - Frontiers in tuberculosis, 2023 - frontiersin.org
Nearly two decades have passed since the first report on autophagy acting as a cell-
autonomous defense against Mycobacterium tuberculosis. This helped usher a new area of …

Type I IFN signaling mediates NET release to promote Mycobacterium tuberculosis replication and granuloma caseation

CS Chowdhury, RL Kinsella, EM Nehls, SK Naik… - Biorxiv, 2022 - biorxiv.org
Neutrophils are the most abundant cell type in airways of tuberculosis patients. Recent
investigations reported induction of neutrophil extracellular traps (NETs) during …

Interactions between CNS and immune cells in tuberculous meningitis

Q Ma, J Chen, X Kong, Y Zeng, Z Chen, H Liu… - Frontiers in …, 2024 - frontiersin.org
The central nervous system (CNS) harbors its own special immune system composed of
microglia in the parenchyma, CNS-associated macrophages (CAMs), dendritic cells …

[HTML][HTML] Early nucleocapsid-specific T cell responses associate with control of SARS-CoV-2 in the upper airways and reduced systemic inflammation before …

TM Eser, O Baranov, M Huth, MIM Ahmed, F Deák… - 2022 - europepmc.org
Despite intensive research since the emergence of SARS-CoV-2, it has remained unclear
precisely which components of the early immune response protect against the development …

Pathogenesis of Post-Tuberculosis Lung Disease: Defining Knowledge Gaps and Research Priorities at the 2nd International Post-Tuberculosis Symposium

SC Auld, AK Barczak, W Bishai… - American Journal of …, 2024 - atsjournals.org
Post-tuberculosis (TB) lung disease (PTLD) is increasingly recognized as a major
contributor to the global burden of chronic lung disease, with recent estimates indicating that …

Effect of TB Treatment on Neutrophil-Derived Soluble Inflammatory Mediators in TB Patients with and without HIV Coinfection

N Sitoe, I Chelene, S Ligeiro, C Castiano, MIM Ahmed… - Pathogens, 2023 - mdpi.com
The mycobacteriological analysis of sputum samples is the gold standard for tuberculosis
diagnosis and treatment monitoring. However, sputum production can be challenging after …

[HTML][HTML] Biochemical markers assessing rate of reparative processes in patients with infiltrative pulmonary tuberculosis

DS Esmedlyaeva, NP Alekseeva… - Russian Journal of …, 2023 - iimmun.ru
The effectiveness of chemotherapy for infiltrative pulmonary tuberculosis (ITL) is determined
by proper timing and adequacy of treatment. The speed of reparative changes in the …

[PDF][PDF] Responses of bovine and human neutrophils to members of the Mycobacterium tuberculosis complex

R Borkute - 2023 - epub.ub.uni-greifswald.de
PMN are one of the most important cells of the innate immune system and are responsible
for fast clearance of invading pathogens in most circumstances. The role of human PMN …