Atherosclerotic cardiovascular diseases (ASCVD), including coronary artery disease,
cerebrovascular disease, and peripheral arterial disease, represent a significant cause of …

Since the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak
emerged, countless efforts are being made worldwide to understand the molecular …

Interleukin-6 is a pleiotropic cytokine regulating different tissues and organs in diverse and
sometimes discrepant ways. The dual and sometime hermetic nature of IL-6 action has been …

Objective: Post-translational modifications of fibrinogen influence the occurrence and
progression of thrombotic diseases. In this systematic review, we assessed the current …

Background. Data on coronavirus disease 2019 (COVID-19) in immunocompromised kidney
transplant recipients (KTR) remain scanty. Although markers of inflammation, cardiac injury …

Muscle regeneration, characterized by the activation and proliferation of satellite cells and
other precursors, is accompanied by an inflammatory response and the remodeling of the …

Altered properties of fibrin clots have been associated with bleeding and thrombotic
disorders, including hemophilia or trauma and heart attack or stroke. Clotting factors, such …

Fibrinogen is one of the key molecular players in haemostasis. Thrombin-mediated release
of fibrinopeptides from fibrinogen converts this soluble protein into a network of fibrin fibres …

The congenital dysfibrinogenemias, most often associated with bleeding disorders,
encompass mutations in the amino-terminal end of fibrinogen α-chain consisting of Gly17 …

The pandemic SARS coronavirus 2 utilizes efficient mechanisms to establish infection and
evade the immune system. Established infection leads to severe inflammation in susceptible …