Persistent infection by EBV is explained by the germinal center model (GCM) which provides
a satisfying and currently the only explanation for EBVs disparate biology. Since the GCM …

Myalgic encephalomyelitis or chronic fatigue syndrome (ME/CFS) affects approximately 1%
of the general population. It is a chronic, disabling, multi-system disease for which there is …

Since the discovery in 1964 of the Epstein–Barr virus (EBV) in African Burkitt lymphoma, this
virus has been associated with a remarkably diverse range of cancer types. Because EBV …

The first human tumor virus was discovered in the middle of the last century by Anthony
Epstein, Bert Achong and Yvonne Barr in African pediatric patients with Burkitt's lymphoma …

Highlights•We summarize and update the germinal center model of Epstein–Barr virus
persistence.•We discuss the weaknesses and strengths of alternate models.•The role of …

Human B cells are the primary targets of Epstein–Barr virus (EBV) infection. In most cases,
EBV infection is asymptomatic because of a highly effective host immune response, but …

Although a pathogenic role for the Epstein-Barr virus (EBV) is largely undisputed for tumors
that are consistently EBV genome positive (eg, nasopharyngeal carcinoma, endemic Burkitt …

The Epstein-Barr virus (EBV) is a ubiquitous pathogen that imparts a significant burden of
disease on the human population. EBV is the primary cause of infectious mononucleosis …

Congenital Zika virus (ZIKV) infection results in neurodevelopmental deficits in up to 14% of
infants born to ZIKV-infected mothers. Neutralizing antibodies are a critical component of …

The Epstein–Barr Virus (EBV) is associated with the development of several diseases,
including infectious mononucleosis (IM), Burkitt's Lymphoma (BL), Nasopharyngeal …