Advanced physical techniques for gene delivery based on membrane perforation

X Du, J Wang, Q Zhou, L Zhang, S Wang, Z Zhang… - Drug …, 2018 - Taylor & Francis
Gene delivery as a promising and valid tool has been used for treating many serious
diseases that conventional drug therapies cannot cure. Due to the advancement of physical …

[HTML][HTML] Efficient delivery of nucleic acid molecules into skin by combined use of microneedle roller and flexible interdigitated electroporation array

D Huang, D Zhao, X Wang, C Li, T Yang, L Du… - Theranostics, 2018 - ncbi.nlm.nih.gov
Rationale: Delivery of nucleic acid molecules into skin remains a main obstacle for various
types of gene therapy or vaccine applications. Here we propose a novel electroporation …

Multi-electrode architecture modeling and optimization for homogeneous electroporation of large volumes of tissue

B López-Alonso, H Sarnago, JM Burdío, P Briz, O Lucía - Energies, 2021 - mdpi.com
Electroporation is a phenomenon that consists of increasing the permeability of the cell
membrane by means of high-intensity electric field application. Nowadays, its clinical …

Multiple-output generator for omnidirectional electroporation and real-time process monitoring

B López-Alonso, H Sarnago, Ó Lucía… - 2021 IEEE Applied …, 2021 - ieeexplore.ieee.org
Irreversible electroporation is a promising cancer treatment technique that takes advantage
of intense electric field application to produce tissue ablation. This paper proposes a new …

Feasibility of electroacoustic tomography: a simulation study

M Wang, A Zarafshani, P Samant… - IEEE transactions on …, 2019 - ieeexplore.ieee.org
The feasibility of electroacoustic tomography (EAT) was investigated for in situ monitoring
the electric field distribution in soft tissue. EAT exploits the phenomenon that the amplitude …

Implementation of Non-Invasive Glucose Monitoring system along with ECG, SPO2 with the help of IoT

CR Kanumuri, KP Varma… - … on Devices, Circuits …, 2022 - ieeexplore.ieee.org
Diabetes mellitus is a metabolic disorder characterized by glucose intolerance that affects
more than 285 million people globally. The traditionally used glucose measurement …

Printed flexible microelectrode for application of nanosecond pulsed electric fields on cells

M Schubert, J Rasche, MM Laurila, T Vuorinen… - Materials, 2019 - mdpi.com
Medical treatment is increasingly benefiting from biomedical microsystems, especially the
trending telemedical application. A promising modality for tumor therapy showed the …

Development of a Wearable Patch Forglucosemonitoring and Insulin Delivery

NN Ahmad - 2024 - search.proquest.com
The development of a closed-loop artificial pancreas system that mimics the function of the
real human pancreas has greatly improved the quality of life for those living with diabetes …

Microneedle roller electrode array (M-REA): A new tool for in vivo low-voltage electric gene delivery

D Huang, D Zhao, Y Huang, Z Liang… - 2018 IEEE Micro Electro …, 2018 - ieeexplore.ieee.org
This paper reports a novel device, so-called microneedle roller electrode array (M-REA), for
minimally invasive in vivo electric gene delivery, which utilizes parallel circular blades with …

Power electronics technologies for electroporation of large tissue volumes

BL Alonso - 2022 - dialnet.unirioja.es
Electroporation is a branch of electrochemistry and electrobiology. These subjects are
focused on the study of the effects of electricity in materials or biological tissues. Specifically …