Humoral immune responses are characterized by complex mixtures of polyclonal antibody
species varying in their isotype, target epitope specificity and affinity. Posttranslational …

Glycomics aims to identify the structure and function of the glycome, the complete set of
oligosaccharides (glycans), produced in a given cell or organism, as well as to identify …

Background The new types of mRNA-containing lipid nanoparticle vaccines BNT162b2 and
mRNA-1273 and the adenovirus-based vaccine AZD1222 were developed against SARS …

Healthy immune responses require efficient protection without excessive inflammation.
Recent discoveries on the degree of fucosylation of a human N-linked glycan at a conserved …

The presence of fucose on IgG1 Asn-297 N-linked glycan is the modification of the human
IgG1 Fc structure with the most significant impact on FcɣRIII affinity. It also significantly …

Immunoglobulins G (IgG) and their Fc gamma receptors (FcγRs) play important roles in our
immune system. The conserved N-glycan in the Fc region of IgG1 impacts interaction of IgG …

Protein glycosylation has a huge impact on biological processes in all domains of life. The
type of glycan present on a recombinant glycoprotein depends on protein intrinsic features …

Infections with Plasmodium falciparum and Plasmodium vivax cause over 600,000 deaths
each year, concentrated in Africa and in young children, but much of the world's population …

Our review summarizes the evidence that COVID-19 can be complicated by SARS-CoV-2
infection of immune cells. This evidence is widespread and accumulating at an increasing …

Most of the membrane molecules involved in immune response are glycosylated. N-glycans
linked to asparagine (Asn) of immune molecules contribute to the protein conformation …