[HTML][HTML] The interplay of NAD and hypoxic stress and its relevance for ageing

J Burtscher, V Denti, JM Gostner, AKH Weiss… - Ageing Research …, 2024 - Elsevier
Nicotinamide adenine dinucleotide (NAD) is an essential regulator of cellular metabolism
and redox processes. NAD levels and the dynamics of NAD metabolism change with …

Sodium-Glucose Cotransporter 2 (SGLT2) Inhibitors: Guardians against Mitochondrial Dysfunction and Endoplasmic Reticulum Stress in Heart Diseases

LTT Pham, S Mangmool… - ACS Pharmacology & …, 2024 - ACS Publications
Sodium-glucose cotransporter 2 (SGLT2) inhibitors are an innovative class of antidiabetic
drugs that provide cardiovascular benefits to both diabetic and nondiabetic patients …

The role of the International Society for Stem Cell Research (ISSCR) guidelines in disease modeling

C Juguilon, JC Wu - Disease Models & Mechanisms, 2024 - journals.biologists.com
Human stem cell-based modeling systems are valuable tools that can greatly improve the
clinical translation of basic research. Importantly, the successful application of human stem …

Conductive Microfibers Improve Stem Cell‐Derived Cardiac Spheroid Maturation

G Gonzalez, TG Molley, E LaMontagne… - … Research Part A, 2025 - Wiley Online Library
ABSTRACT Conventional two‐dimensional (2D) cardiomyocyte differentiation protocols
create cells with limited maturity, which impairs their predictive capacity and has driven …

Digital Light Processing 3D Printing enables High Throughput Fabrication of Human Engineered Heart Tissues for Disease Modeling

AP Dhand, MA Juarros, TG Martin… - bioRxiv, 2024 - biorxiv.org
3D in vitro engineered heart tissue (EHT) models recapitulate aspects of native cardiac
physiology but are often limited by scalability, cost, and reproducibility. Here, we report a …

Tachikardiomiopatija. Klinikinis atvejis ir literatūros apžvalga

K Ratautė - 2024 - epublications.vu.lt
Abstract [eng] Introduction. Tachycardia-induced cardiomyopathy is a condition, resulting
from rapid and/or asynchronous/irregular myocardial contraction, manifesting as left …

FSH exacerbates bone loss by promoting osteoclast energy metabolism through the CREB-MDH2-NAD+ axis

J Chen, Y Liao, Y Sheng, H Yao, T Li, Z He, WWY Ye… - Metabolism, 2025 - Elsevier
Aims Osteoclast energy metabolism is a promising target for treating diseases characterized
by high osteoclast activity, such as osteoporosis. However, the regulatory factors involved in …