Survey on the recent advances in 4-hydroxyphenylpyruvate dioxygenase (HPPD) inhibition by diketone and triketone derivatives and congeneric compounds …
The serendipitous discovery of the HPPD inhibitors from allelopathic plants opened the way
for searching new and effective herbicidal agents by application of classical hit-to-lead …
for searching new and effective herbicidal agents by application of classical hit-to-lead …
Recent research progress and outlook in agricultural chemical discovery based on quinazoline scaffold
J Chen, Y Wang, X Luo, Y Chen - Pesticide Biochemistry and Physiology, 2022 - Elsevier
The discovery of new scaffolds and targets for pesticides is still a huge challenge facing the
sustainable development of modern agriculture. In recent years, quinazoline derivatives …
sustainable development of modern agriculture. In recent years, quinazoline derivatives …
[HTML][HTML] Design of an HPPD fluorescent probe and visualization of plant responses to abiotic stress
X Zeng, Y Huang, J Dong, X Ma, JX Nan, W Chen… - Advanced …, 2022 - Elsevier
The upregulation of 4-hydroxyphenylpyruvate dioxygenase (HPPD) can protect plants from
adverse abiotic stress. Therefore, studying the changes of HPPD under abiotic stress is …
adverse abiotic stress. Therefore, studying the changes of HPPD under abiotic stress is …
Synthesis and herbicidal activity of novel pyrazole aromatic ketone analogs as HPPD inhibitor
Q Fu, PP Cai, L Cheng, LK Zhong… - Pest management …, 2020 - Wiley Online Library
Abstract BACKGROUND 4‐Hydroxyphenylpyruvate dioxygenase (HPPD, EC 1.13. 11.27)
has been a good target for herbicide discovery. In order to discover novel HPPD herbicides …
has been a good target for herbicide discovery. In order to discover novel HPPD herbicides …
Pharmacophore-oriented discovery of novel 1, 2, 3-benzotriazine-4-one derivatives as potent 4-hydroxyphenylpyruvate dioxygenase inhibitors
YC Yan, W Wu, GY Huang, WC Yang… - Journal of Agricultural …, 2022 - ACS Publications
4-Hydroxyphenylpyruvate dioxygenase (HPPD) is a functional protein existing in almost all
aerobic organisms. In the field of agricultural chemicals, HPPD is acknowledged to be one of …
aerobic organisms. In the field of agricultural chemicals, HPPD is acknowledged to be one of …
Design, synthesis, herbicidal activity and CoMFA of aryl-formyl piperidinone HPPD inhibitors
Y Fu, M Wang, LX Zhao, SQ Zhang, YX Liu… - Pesticide Biochemistry …, 2021 - Elsevier
Isoxazole, nicotinic acid and benzoic acid are important components in many natural
products and useful synthons to build macrostructures having valuable biological activities …
products and useful synthons to build macrostructures having valuable biological activities …
Design, synthesis, SAR and molecular docking of novel green niacin-triketone HPPD inhibitor
Y Fu, SQ Zhang, YX Liu, JY Wang, S Gao… - Industrial Crops and …, 2019 - Elsevier
Hydroxyphenylpyruvate dioxygenase (EC 1.13. 11.27, HPPD) is a very important target for
the discovery of novel bleaching herbicides. In order to discover novel triketone green HPPD …
the discovery of novel bleaching herbicides. In order to discover novel triketone green HPPD …
Synthesis and Herbicidal Activity of Triketone-Aminopyridines as Potent p-Hydroxyphenylpyruvate Dioxygenase Inhibitors
JX Nan, JF Yang, HY Lin, YC Yan… - Journal of Agricultural …, 2021 - ACS Publications
Exploring novel p-hydroxyphenylpyruvate dioxygenase (EC 1.13. 11.27, HPPD) inhibitors
has become one of the most promising research directions in herbicide innovation. On the …
has become one of the most promising research directions in herbicide innovation. On the …
Structure-guided discovery of silicon-containing subnanomolar inhibitor of hydroxyphenylpyruvate dioxygenase as a potential herbicide
RY Qu, JX Nan, YC Yan, Q Chen… - Journal of Agricultural …, 2021 - ACS Publications
4-Hydroxyphenylpyruvate dioxygenase (HPPD, EC 1.13. 11.27) has been recognized as
one of the most promising targets in the field of herbicide innovation considering the severity …
one of the most promising targets in the field of herbicide innovation considering the severity …
Caffeine and caffeine-containing pharmaceuticals as promising inhibitors for 3-chymotrypsin-like protease of SARS-CoV-2
AO Elzupir - Journal of Biomolecular Structure and Dynamics, 2022 - Taylor & Francis
In December 2019, a new coronavirus named severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) led to the outbreak of a pulmonary disease called COVID-19 …
coronavirus 2 (SARS-CoV-2) led to the outbreak of a pulmonary disease called COVID-19 …