Alzheimer's disease as a synaptopathy: Evidence for dysfunction of synapses during disease progression

S Meftah, J Gan - Frontiers in Synaptic Neuroscience, 2023 - frontiersin.org
The synapse has consistently been considered a vulnerable and critical target within
Alzheimer's disease, and synapse loss is, to date, one of the main biological correlates of …

[HTML][HTML] Gamma oscillations in Alzheimer's disease and their potential therapeutic role

A Traikapi, N Konstantinou - Frontiers in systems neuroscience, 2021 - frontiersin.org
Despite decades of research, Alzheimer's Disease (AD) remains a lethal neurodegenerative
disorder for which there are no effective treatments. This review examines the latest …

Forty-hertz light stimulation does not entrain native gamma oscillations in Alzheimer's disease model mice

M Soula, A Martín-Ávila, Y Zhang, A Dhingra… - Nature …, 2023 - nature.com
There is a demand for noninvasive methods to ameliorate disease. We investigated whether
40-Hz flickering light entrains gamma oscillations and suppresses amyloid-β in the brains of …

[HTML][HTML] An update on the use of gamma (multi) sensory stimulation for Alzheimer's disease treatment

V Manippa, A Palmisano, M Filardi, D Vilella… - Frontiers in Aging …, 2022 - frontiersin.org
Alzheimer's disease (AD) is characterized by reduced fast brain oscillations in the gamma
band (γ,> 30 Hz). Several animal studies show that inducing gamma oscillations through …

[HTML][HTML] The hearing hippocampus

AJ Billig, M Lad, W Sedley, TD Griffiths - Progress in neurobiology, 2022 - Elsevier
The hippocampus has a well-established role in spatial and episodic memory but a broader
function has been proposed including aspects of perception and relational processing …

The medial septum as a potential target for treating brain disorders associated with oscillopathies

Y Takeuchi, AJ Nagy, L Barcsai, Q Li… - Frontiers in Neural …, 2021 - frontiersin.org
The medial septum (MS), as part of the basal forebrain, supports many physiological
functions, from sensorimotor integration to cognition. With often reciprocal connections with …

Gamma oscillations and application of 40‐Hz audiovisual stimulation to improve brain function

X Chen, X Shi, Y Wu, Z Zhou, S Chen, Y Han… - Brain and …, 2022 - Wiley Online Library
Background Audiovisual stimulation, such as auditory stimulation, light stimulation, and
audiovisual combined stimulation, as a non‐invasive stimulation, which can induce gamma …

Episodic memory effects of gamma frequency precuneus transcranial magnetic stimulation in Alzheimer's disease: A randomized multiple baseline study

A Traikapi, I Kalli, A Kyriakou… - Journal of …, 2023 - Wiley Online Library
Episodic memory decline is the prominent neuropsychological feature of typical Alzheimer's
Disease (AD), for which current treatments have a limited clinical response. Recently …

The role of aberrant neural oscillations in the hippocampal-medial prefrontal cortex circuit in neurodevelopmental and neurological disorders

N Shing, MC Walker, P Chang - Neurobiology of Learning and Memory, 2022 - Elsevier
The hippocampus (HPC) and medial prefrontal cortex (mPFC) have well-established roles in
cognition, emotion, and sensory processing. In recent years, interests have shifted towards …

Sharpening working memory with real-time electrophysiological brain signals: which neurofeedback paradigms work?

Y Jiang, W Jessee, S Hoyng, S Borhani… - Frontiers in Aging …, 2022 - frontiersin.org
Growing evidence supports the idea that the ultimate biofeedback is to reward sensory
pleasure (eg, enhanced visual clarity) in real-time to neural circuits that are associated with …