Precise plant genome editing using base editors and prime editors

KA Molla, S Sretenovic, KC Bansal, Y Qi - Nature Plants, 2021 - nature.com
The development of CRISPR–Cas systems has sparked a genome editing revolution in
plant genetics and breeding. These sequence-specific RNA-guided nucleases can induce …

Genome editing with CRISPR–Cas nucleases, base editors, transposases and prime editors

AV Anzalone, LW Koblan, DR Liu - Nature biotechnology, 2020 - nature.com
The development of new CRISPR–Cas genome editing tools continues to drive major
advances in the life sciences. Four classes of CRISPR–Cas-derived genome editing agents …

Conventional and molecular techniques from simple breeding to speed breeding in crop plants: recent advances and future outlook

S Ahmar, RA Gill, KH Jung, A Faheem… - International journal of …, 2020 - mdpi.com
In most crop breeding programs, the rate of yield increment is insufficient to cope with the
increased food demand caused by a rapidly expanding global population. In plant breeding …

CRISPR/Cas system: recent advances and future prospects for genome editing

H Manghwar, K Lindsey, X Zhang, S Jin - Trends in plant science, 2019 - cell.com
Genome editing (GE) has revolutionized biological research through the new ability to
precisely edit the genomes of living organisms. In recent years, various GE tools have been …

A comprehensive overview of cotton genomics, biotechnology and molecular biological studies

X Wen, Z Chen, Z Yang, M Wang, S Jin, G Wang… - Science China Life …, 2023 - Springer
Cotton is an irreplaceable economic crop currently domesticated in the human world for its
extremely elongated fiber cells specialized in seed epidermis, which makes it of high …

Precision genome editing using cytosine and adenine base editors in mammalian cells

TP Huang, GA Newby, DR Liu - Nature protocols, 2021 - nature.com
Genome editing has transformed the life sciences and has exciting prospects for use in
treating genetic diseases. Our laboratory developed base editing to enable precise and …

Base editing in crops: current advances, limitations and future implications

R Mishra, RK Joshi, K Zhao - Plant Biotechnology Journal, 2020 - Wiley Online Library
Targeted mutagenesis via genome‐editing technologies holds great promise in developing
improved crop varieties to meet future demands. Point mutations or single nucleotide …

Next-generation breeding strategies for climate-ready crops

A Razzaq, P Kaur, N Akhter, SH Wani… - Frontiers in Plant …, 2021 - frontiersin.org
Climate change is a threat to global food security due to the reduction of crop productivity
around the globe. Food security is a matter of concern for stakeholders and policymakers as …

Plant base editing and prime editing: the current status and future perspectives

J Li, C Zhang, Y He, S Li, L Yan, Y Li… - Journal of Integrative …, 2023 - Wiley Online Library
Precise replacement of an allele with an elite allele controlling an important agronomic trait
in a predefined manner by gene editing technologies is highly desirable in crop …

Host-mediated gene engineering and microbiome-based technology optimization for sustainable agriculture and environment

N Thakur, M Nigam, NA Mann, S Gupta… - Functional & Integrative …, 2023 - Springer
The agricultural sector and environmental safety both work hand in hand to promote
sustainability in important issues like soil health, plant nutrition, food safety, and security …