Cardiovascular stents: a review of past, current, and emerging devices

A Scafa Udriște, AG Niculescu, AM Grumezescu… - Materials, 2021 - mdpi.com
One of the leading causes of morbidity and mortality worldwide is coronary artery disease, a
condition characterized by the narrowing of the artery due to plaque deposits. The standard …

The mechanisms of restenosis and relevance to next generation stent design

J Clare, J Ganly, CA Bursill, H Sumer, P Kingshott… - Biomolecules, 2022 - mdpi.com
Stents are lifesaving mechanical devices that re-establish essential blood flow to the
coronary circulation after significant vessel occlusion due to coronary vessel disease or …

A tailored extracellular matrix (ECM)-Mimetic coating for cardiovascular stents by stepwise assembly of hyaluronic acid and recombinant human type III collagen

L Yang, H Wu, L Lu, Q He, B Xi, H Yu, R Luo, Y Wang… - Biomaterials, 2021 - Elsevier
Collagen, a central component of the extracellular matrix (ECM), has been widely applied in
tissue engineering, among others, for wound healing or bone and nerve regeneration …

Gas station in blood vessels: An endothelium mimicking, self-sustainable nitric oxide fueling stent coating for prevention of thrombosis and restenosis

J Rao, X Mou, Y Mo, HP Bei, L Wang, CY Tang, KH Yiu… - Biomaterials, 2023 - Elsevier
Stenting is the primary treatment for vascular obstruction-related cardiovascular diseases,
but it inevitably causes endothelial injury which may lead to severe thrombosis and …

Epigallocatechin gallate mediated sandwich-like coating for mimicking endothelium with sustained therapeutic nitric oxide generation and heparin release

B Zhang, R Yao, C Hu, MF Maitz, H Wu, K Liu, L Yang… - Biomaterials, 2021 - Elsevier
In-stent restenosis after stenting is generally characterized by an inflammatory response,
excessive proliferation of smooth muscle cells, and delayed healing of the endothelium …

Surface engineering of bioactive coatings for improved stent hemocompatibility: A comprehensive review

AS Raikar, S Priya, SP Bhilegaonkar, SN Somnache… - Materials, 2023 - mdpi.com
Cardiovascular diseases continue to be a major contributor to illness and death on a global
scale, and the implementation of stents has given rise to a revolutionary transformation in …

[HTML][HTML] Anti-fouling plus: Engineered stent coating with inflammation-regulation capability enables enhanced tissue healing

H Yan, Y Qin, Y Li, Y An, H Wu, C Chen, L Yang… - Composites Part B …, 2023 - Elsevier
Coagulation, inflammation, and hyperplasia frequently restrict the effectiveness of
cardiovascular stents. It is critical to modify stent surfaces to allow for in situ tissue healing …

Restenosis after coronary stent implantation: cellular mechanisms and potential of endothelial progenitor cells (a short guide for the interventional cardiologist)

T Gori - Cells, 2022 - mdpi.com
Coronary stents are among the most common therapies worldwide. Despite significant
improvements in the biocompatibility of these devices throughout the last decades, they are …

An extracellular matrix-mimetic coating with dual bionics for cardiovascular stents

N Chen, M Li, H Wu, Y Qin, J Wang, K Xu… - Regenerative …, 2023 - academic.oup.com
Anti-inflammation and anti-coagulation are the primary requirements for cardiovascular
stents and also the widely accepted trajectory for multi-functional modification. In this work …

Surface engineering at the nanoscale: A way forward to improve coronary stent efficacy

AM Cherian, SV Nair, V Maniyal, D Menon - APL bioengineering, 2021 - pubs.aip.org
Coronary in-stent restenosis and late stent thrombosis are the two major inadequacies of
vascular stents that limit its long-term efficacy. Although restenosis has been successfully …