Nuclear-and membrane-initiated estrogen signaling cooperate to orchestrate the pleiotropic
effects of estrogens. Classical estrogen receptors (ERs) act transcriptionally and govern the …

Estrogen binding to estrogen receptors (ESR) triggers signaling cascades within cells.
Historically, a major emphasis has been characterizing estrogen-induced genomic actions …

Interest in female sexual behavior and reproduction is likely as old as our species. Indeed,
one of the oldest known medical texts, the Kahun Papyrus, found near the pyramid in El …

It has long been known that the estrogen, 17β-estradiol (17β-E), plays a central role for
female reproductive physiology and behavior. Numerous studies have established the …

The estrogen receptor and glucocorticoid receptor are members of the nuclear receptor
superfamily that can signal using both non-genomic and genomic transcriptional modes …

Sex and aggression are well studied examples of social behaviours that are common to
most animals and are mediated by an evolutionary conserved group of interconnected …

Background The clinical significance of progesterone receptor (PgR) expression in estrogen
receptor-negative (ER–) breast cancer is controversial. Herein, we systemically investigate …

Background/Aims: Estrogens are important effectors of reproduction and are critical for
upregulating female reproductive behavior or lordosis in females. In addition to the …

Efficacy of soy isoflavones to promote semen quality by improving antioxidant parameters in
Xinong Saanen goats was explored. Soy isoflavones (SI), regulator of steroid hormone …

Progesterone receptor (PR) activation in the ventrolateral division of the hypothalamic
ventromedial nucleus (VMN vl) is essential for promoting female sexual behavior. Estrogen …