The HLA-G gene displays several peculiarities that are distinct from those of classical HLA
class I genes. The unique structure of the HLA-G molecule permits a restricted peptide …

HLA-G has a relevant role in immune response regulation. The overall structure of the HLA-
G coding region has been maintained during the evolution process, in which most of its …

Human leukocyte antigen G (HLA-G) belongs to the family of non-classical HLA class I
genes, located within the major histocompatibility complex (MHC). HLA-G has been the …

Soluble human leukocyte antigen‐G (sHLA‐G) functions as a multiple immunoregulator. A
14 bp insertion (+ 14 bp)/deletion (− 14 bp) polymorphism in exon 8 of the HLA‐G gene has …

Methotrexate is a folate analog that is used in the treatment of cancers (eg acute
lymphoblastic leukemia, non-Hodgkin lymphoma, osteosarcoma, and colon cancer) and …

Human leukocyte antigen (HLA)-G molecule, a non-classical HLA-Ib molecule, is less
polymorphic when compared to classical HLA class I molecules. Human leukocyte antigen …

Human leukocyte antigen‐G (HLA‐G) is a low polymorphic nonclassical HLA‐I molecule
restrictively expressed and with suppressive functions. HLA‐G gene products are quite …

Objective. Methotrexate (MTX) is an effective therapy for rheumatoid arthritis (RA) but it is
also associated with toxicity. Pharmacogenetics is the systematic evaluation of the role of …

HLA-G is a class Ib HLA which has gained much attention due to its multiple functions on the
immune system. HLA-G exerts several immunomodulatory effects, being beneficially …

Human leukocyte antigen-G (HLA-G) is a nonclassical class Ib molecule belonging to the
major histocompatibility complex. HLA-G appears to play a role in the suppression of …