In the brain, cell adhesion molecules (CAMs) are critical for neurite outgrowth, axonal
fasciculation, neuronal survival and migration, and synapse formation and maintenance …

Background Viral encephalitis increases later-life risk of Alzheimer's disease (AD) by a factor
of 31. Methods To further evaluate this finding, we examined the relationship of West Nile …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the most
common cause of dementia in the elderly worldwide. The exact etiology of AD, particularly …

The accumulation of β‐amyloid in Alzheimer's disease greatly impacts neuronal health and
synaptic function. To maintain network stability in the face of altered synaptic activity …

Dysfunctional lactate metabolism in the brain has been implicated in neuroinflammation, Aβ
deposition, and cell disturbance, all of which play a significant role in the pathogenesis of …

Background Schizophrenia is a mental disorder that causes considerable morbidity, whose
risk largely results from genetic factors. Setd1a is a gene implicated in schizophrenia …

The accumulation of β-amyloid in Alzheimer's disease greatly impacts neuronal health and
synaptic function. To maintain network stability in the face of altered synaptic activity …

Pain is a dynamic and nonlinear experience shaped by injury and contextual factors,
including expectations of future pain or relief. While mu opioid receptors are central to the …

Background Abnormal immunity in the periphery has been reported in the pathogenesis of
Alzheimer's disease (AD). Objective In this study, blood transcriptome analyses of patients …

Murine models of Alzheimer's disease (AD) are crucial for elucidating disease mechanisms
but have limitations in fully representing AD molecular complexities. We comprehensively …