Protic ionic liquids: evolving structure–property relationships and expanding applications

TL Greaves, CJ Drummond - Chemical reviews, 2015 - ACS Publications
The field of ionic liquds is growing significantly, with an increased focus on developing ionic
liquds for specific applications, along with fundamental research. By definition, ionic liquids …

[HTML][HTML] Ionic liquids as protein stabilizers for biological and biomedical applications: A review

NV Veríssimo, FA Vicente, RC de Oliveira… - Biotechnology …, 2022 - Elsevier
Biotechnology has revolutionized science and health care by providing new biomolecules
with biological and medical applications. However, the low stability of several life-saving …

Biocompatibility of ionic liquids towards protein stability: A comprehensive overview on the current understanding and their implications

A Kumar, M Bisht, P Venkatesu - International journal of biological …, 2017 - Elsevier
Over the past years since the discovery of ionic liquids (ILs), there is an increased demand
to consider ILs as novel biocompatible co-solvents for proteins. Due to their tunable physical …

Protein aggregation and crystallization with ionic liquids: Insights into the influence of solvent properties

Q Han, SJ Brown, CJ Drummond, TL Greaves - Journal of Colloid and …, 2022 - Elsevier
Ionic liquids (ILs) have been used in solvents for proteins in many applications, including
biotechnology, pharmaceutics, and medicine due to their tunable physicochemical and …

Direct evidence of confined water in room-temperature ionic liquids by complementary use of small-angle X-ray and neutron scattering

H Abe, T Takekiyo, M Shigemi… - The Journal of …, 2014 - ACS Publications
The direct evidence of confined water (“water pocket”) inside hydrophilic room-temperature
ionic liquids (RTILs) was obtained by complementary use of small-angle X-ray scattering …

Cryopreservation of Proteins Using Ionic Liquids: A Case Study of Cytochrome c

T Takekiyo, Y Ishikawa… - The Journal of Physical …, 2017 - ACS Publications
Aqueous ionic liquid (IL) solutions form a glassy state at 77 K over a wide concentration of
ILs. They have potential as novel cryopreservation/refolding solvents for proteins. However …

Aromatic vs alicyclic: hydrophobicity of the ionic liquid on protein stability and fibril formation

P Kushwaha, NP Prabhu - Journal of Molecular Liquids, 2024 - Elsevier
Ionic liquids (ILs) are environment-friendly solvents with potential applications in
biochemical reactions and as pharmaceutical ingredients. They are used to stabilize …

Endeavour to simplify the frustrated concept of protein-ammonium family ionic liquid interactions

I Jha, P Venkatesu - Physical Chemistry Chemical Physics, 2015 - pubs.rsc.org
The large amount of attention earned by ionic liquids (ILs) in the various physical and
chemical sciences has been attributed to their unique, designer nature. In the past few …

Ionic liquids in protein amyloidogenesis: a brief screenshot of the state-of-the-art

VVS Pillai, A Benedetto - Biophysical Reviews, 2018 - Springer
Ionic liquids (ILs) are a vast class of organic non-aqueous electrolytes whose interaction
with biomolecules is receiving great attention for potential applications in bio-nano …

Imidazolium-based ionic liquids with increasing alkyl chain length of cations decrease the stability and fibrillation propensity of lysozyme

P Kushwaha, NP Prabhu - New Journal of Chemistry, 2022 - pubs.rsc.org
Ionic liquids (ILs) are neoteric solvents with a wide range of applications. Interaction of ILs
with proteins alters their stability and self-aggregation. The present work analyses the effect …