RNA delivery by extracellular vesicles in mammalian cells and its applications

K O'Brien, K Breyne, S Ughetto, LC Laurent… - … reviews Molecular cell …, 2020 - nature.com
The term 'extracellular vesicles' refers to a heterogeneous population of vesicular bodies of
cellular origin that derive either from the endosomal compartment (exosomes) or as a result …

When nano meets plants: A review on the interplay between nanoparticles and plants

J Hu, Y Xianyu - Nano Today, 2021 - Elsevier
The interplay between nanoparticles (NPs) and plants greatly promotes the development of
research fields like nanotechnology, agriculture, food science, electrical engineering and …

Plant-derived extracellular vesicles (PDEVs) in nanomedicine for human disease and therapeutic modalities

Z Xu, Y Xu, K Zhang, Y Liu, Q Liang, A Thakur… - Journal of …, 2023 - Springer
Background The past few years have witnessed a significant increase in research related to
plant-derived extracellular vesicles (PDEVs) in biological and medical applications. Using …

Advances in colon-targeted nano-drug delivery systems: challenges and solutions

M Naeem, UA Awan, F Subhan, J Cao… - Archives of pharmacal …, 2020 - Springer
Nano-drug delivery systems (NDDS) for colon-targeted drug delivery are an active area of
research on local diseases affecting the colon, such as ulcerative colitis, Crohn's disease …

Arrowtail RNA for ligand display on ginger exosome-like nanovesicles to systemic deliver siRNA for cancer suppression

Z Li, H Wang, H Yin, C Bennett, H Zhang, P Guo - Scientific reports, 2018 - nature.com
Exosomes have shown increasing potential as delivery vesicles for therapy, but challenges
like cost/yield, drug payload, and targeting specificity still exist. Plant derived exosome-like …

Plant derived edible nanoparticles as a new therapeutic approach against diseases

M Zhang, E Viennois, C Xu, D Merlin - Tissue barriers, 2016 - Taylor & Francis
In plant cells, nanoparticles containing miRNA, bioactive lipids and proteins serve as
extracellular messengers to mediate cell-cell communication in a manner similar to the …

Apple derived exosomes improve collagen type I production and decrease MMPs during aging of the skin through downregulation of the NF-κB pathway as mode of …

M Trentini, I Zanolla, F Zanotti, E Tiengo, D Licastro… - Cells, 2022 - mdpi.com
Skin ageing is strictly related to chronic inflammation of the derma and the decay of
structural proteins of the extracellular matrix. Indeed, it has become common practice to refer …

Plant-derived edible nanoparticles and miRNAs: emerging frontier for therapeutics and targeted drug-delivery

S Iravani, RS Varma - ACS Sustainable Chemistry & Engineering, 2019 - ACS Publications
Rigorous and timely studies have been conducted to develop natural and green
nanomedicines wherein plant-derived edible nanoparticles (PDENs) have a great potential …

The potentiality of plant-derived nanovesicles in human health—a comparison with human exosomes and artificial nanoparticles

M Logozzi, R Di Raimo, D Mizzoni, S Fais - International journal of …, 2022 - mdpi.com
Research in science and medicine is witnessing a massive increases in literature
concerning extracellular vesicles (EVs). From a morphological point of view, EVs include …

RNA biomarkers: frontier of precision medicine for cancer

X Xi, T Li, Y Huang, J Sun, Y Zhu, Y Yang, ZJ Lu - Non-coding RNA, 2017 - mdpi.com
As an essential part of central dogma, RNA delivers genetic and regulatory information and
reflects cellular states. Based on high-throughput sequencing technologies, cumulating data …