Bax/Bcl-2 cascade is regulated by the EGFR pathway: therapeutic targeting of non-small cell lung cancer

M Alam, S Alam, A Shamsi, M Adnan… - Frontiers in …, 2022 - frontiersin.org
Non-small cell lung carcinoma (NSCLC) comprises 80%–85% of lung cancer cases. EGFR
is involved in several cancer developments, including NSCLC. The EGFR pathway …

Therapeutic implications of black seed and its constituent thymoquinone in the prevention of cancer through inactivation and activation of molecular pathways

AH Rahmani, MA Alzohairy, MA Khan… - Evidence‐Based …, 2014 - Wiley Online Library
The cancer is probably the most dreaded disease in both men and women and also major
health problem worldwide. Despite its high prevalence, the exact molecular mechanisms of …

Immunomodulatory and anti-inflammatory effects of thymoquinone

H Shaterzadeh-Yazdi, MF Noorbakhsh… - … Current Drug Targets …, 2018 - ingentaconnect.com
Background: The immunomodulatory properties of Nigella sativa seed, as a basis of its
clinical applications by many cultures have been reviewed. Thymoquinone (TQ) is one of the …

[PDF][PDF] Nigella sativa and its active constituents thymoquinone shows pivotal role in the diseases prevention and treatment

AH Rahmani, SM Aly - Asian J Pharm Clin Res, 2015 - Citeseer
Medicinal plants and its constituents used as therapeutics drugs in the health management
since ancient time and large population of the world relies on traditional medicine for …

The effects of Nigella sativa on thyroid function, serum Vascular Endothelial Growth Factor (VEGF)–1, Nesfatin-1 and anthropometric features in patients with …

MA Farhangi, P Dehghan, S Tajmiri… - BMC complementary and …, 2016 - Springer
Background Hashimoto's thyroiditis is an autoimmune disorder and the most common cause
of hypothyroidism. The use of Nigella sativa, a potent herbal medicine, continues to increase …

Black Seed (Nigella sativa): A Favourable Alternative Therapy for Inflammatory and Immune System Disorders

OO Ojueromi, G Oboh, AO Ademosun - Inflammopharmacology, 2022 - Springer
In the recent years, various food additives, medicinal plants, and their bioactive components
have been utilized in anti-inflammatory and immunomodulatory therapy. Nigella sativa is a …

Therapeutic potentials of Nigella sativa preparations and its constituents in the management of diabetes and its complications in experimental animals and patients …

MR Mahmoodi, M Mohammadizadeh - Complementary therapies in …, 2020 - Elsevier
Objective The purpose of this up-to-date comprehensive systematic review was to evaluate
and summarize all research studies in the field in order to clarify the magnitude of Nigella …

[HTML][HTML] A nutraceutical combination of Cinnamomum cassia & Nigella sativa for Type 1 diabetes mellitus

G Kaur, M Invally, MK Khan, P Jadhav - Journal of Ayurveda and integrative …, 2018 - Elsevier
Background Nigella sativa (black cumin) and Cinnamomum cassia (Cinnamon) are an
integral part of the Indian diet, and have also been sourced in the ayurveda, the traditional …

Thymoquinone a potential therapeutic molecule from the plant Nigella sativa: role of colloidal carriers in its effective delivery

P Negi, C Rathore, G Sharma, B Singh… - Recent patents on …, 2018 - ingentaconnect.com
Background: From the past few decades, remarkable awareness has laid on the use of
herbal medicines in pharmaceutical research. Thymoquinone (TQ), the main chemical …

The Impact of Nigella sativa Essential Oil on T Cells in Women with Hashimoto's Thyroiditis

K Ciesielska-Figlon, K Wojciechowicz, A Daca… - Antioxidants, 2023 - mdpi.com
Background: Hashimoto's thyroiditis (HT) is an autoimmune disease mediated by T cells. It is
characterized by the presence of thyroid autoantibodies in the serum, such as anti-thyroid …